Fam151b MGI Mouse Gene Detail - MGI:1921192 - family with sequence similarity 151, member B

Symbol

Fam151b
Name

family with sequence similarity 151, member B
Synonyms

4930405M20Rik

Feature Type

protein coding gene
IDs

MGI:1921192
NCBI Gene: 73942
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr13:92586133-92620523 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 47.70 cM
Mapping Data

1 experiment

SNPs within 2kb

1243 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1921192	protein coding gene	Chr13:92586128-92620539 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0020816	protein coding gene	Chr13:93752304-93787770 (-)
A/J	MGP_AJ_G0020770	protein coding gene	Chr13:90289096-90327069 (-)
AKR/J	MGP_AKRJ_G0020743	protein coding gene	Chr13:93017508-93052726 (-)
BALB/cJ	MGP_BALBcJ_G0020766	protein coding gene	Chr13:90927109-90961576 (-)
C3H/HeJ	MGP_C3HHeJ_G0020560	protein coding gene	Chr13:92728095-92765878 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0021203	protein coding gene	Chr13:96607161-96642530 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018770	protein coding gene	Chr13:86208541-86242454 (-)
CAST/EiJ	MGP_CASTEiJ_G0020079	protein coding gene	Chr13:91989813-92022258 (-)
CBA/J	MGP_CBAJ_G0020519	protein coding gene	Chr13:100448702-100491496 (-)
DBA/2J	MGP_DBA2J_G0020644	protein coding gene	Chr13:90041401-90074844 (-)
FVB/NJ	MGP_FVBNJ_G0020624	protein coding gene	Chr13:88865505-88899918 (-)
LP/J	MGP_LPJ_G0020717	protein coding gene	Chr13:93874222-93910148 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020653	protein coding gene	Chr13:100947688-100982370 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021243	protein coding gene	Chr13:92424571-92460338 (-)
PWK/PhJ	MGP_PWKPhJ_G0019831	protein coding gene	Chr13:88793524-88827219 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0019655	protein coding gene	Chr13:88684150-88718743 (-)
WSB/EiJ	MGP_WSBEiJ_G0020136	protein coding gene	Chr13:92904653-92940278 (-)

Human Ortholog

FAM151B, family with sequence similarity 151 member B

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

FAM151B, family with sequence similarity 151 member B
Synonyms

UNQ9217
Links

HGNC:33716

NCBI Gene ID: 167555

neXtProt AC: NX_Q6UXP7

UniProt: Q6UXP7
Chr Location

5q14.1; chr5:80487969-80542563 (+) GRCh38

MGI Vertebrate Homology

Fam151b stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: FAM151B
Gene Tree

Fam151b

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Phenotype Summary

10 phenotypes from 1 allele in 2 genetic backgrounds
4 phenotypes from multigenic genotypes
9 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

4
Chemically induced (other)

1
Targeted

3
Genomic Mutations

1 involving Fam151b
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

20 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Homozygous knockout results in photoreceptor outer segment degeneration shortly after eye opening.

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All GO Annotations

2
GO References

2

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

709
Tissues

3
cDNA Data

8
Literature Summary

1

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase fam151b

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All Sequences

33
RefSeq

2
UniProt

2
CCDS

CCDS49327.1

Ensembl

ENSMUSG00000034334 (Evidence)
NCBI Gene

73942

			Length	Strain/Species	Flank
genomic	ENSMUSG00000034334	Ensembl Gene Model \| MGI Sequence Detail	34391	C57BL/6J	± kb
transcript	ENSMUST00000040106	Ensembl \| MGI Sequence Detail	1152	Not Applicable
polypeptide	ENSMUSP00000045024	Ensembl \| MGI Sequence Detail	279	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000031620 protein FAM151B

(term hierarchy)
InterPro Domains

IPR019356 Menorin

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All nucleic 8

cDNA 8

Microarray probesets 3

Summaries

All 30

Developmental Gene Expression 1

Gene Ontology 2

Phenotypes 9
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Fam151b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr123433	Chr13:92620504-92620545 (-)	-2 bp
Tssr123432	Chr13:92620459-92620494 (-)	46 bp
Tssr123431	Chr13:92587764-92587784 (-)	32,749 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24