Crct1 Gene Detail

Summary

• Symbol
  Crct1
• Name
  cysteine-rich C-terminal 1
• Synonyms
  2300002G24Rik, Nice-1

• Feature Type
  protein coding gene
• IDs
  MGI:1921425
  NCBI Gene: 74175
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr3:92921512-92922993 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 3, 40.14 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  119 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1921425	protein coding gene	Chr3:92921512-92922994 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0027528	protein coding gene	Chr3:93491785-93493267 (-)
A/J	MGP_AJ_G0027492	protein coding gene	Chr3:90573686-90575168 (-)
AKR/J	MGP_AKRJ_G0027460	protein coding gene	Chr3:92673810-92675292 (-)
BALB/cJ	MGP_BALBcJ_G0027501	protein coding gene	Chr3:90357575-90359057 (-)
C3H/HeJ	MGP_C3HHeJ_G0027240	protein coding gene	Chr3:92888329-92889811 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0027944	protein coding gene	Chr3:97051567-97053049 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0025293	protein coding gene	Chr3:87178823-87180335 (-)
CAST/EiJ	MGP_CASTEiJ_G0026688	protein coding gene	Chr3:92319659-92321141 (-)
CBA/J	MGP_CBAJ_G0027215	protein coding gene	Chr3:100388163-100389645 (-)
DBA/2J	MGP_DBA2J_G0027353	protein coding gene	Chr3:89892785-89894267 (-)
FVB/NJ	MGP_FVBNJ_G0027322	protein coding gene	Chr3:88030132-88031614 (-)
LP/J	MGP_LPJ_G0027462	protein coding gene	Chr3:94725076-94726558 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0027346	protein coding gene	Chr3:106677227-106678709 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0028003	protein coding gene	Chr3:92416024-92417506 (-)
PWK/PhJ	MGP_PWKPhJ_G0026416	protein coding gene	Chr3:89764603-89766085 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0026236	protein coding gene	Chr3:90757219-90758700 (-)
WSB/EiJ	MGP_WSBEiJ_G0026770	protein coding gene	Chr3:92789904-92791386 (-)

Homology

• Human Ortholog
  CRCT1, cysteine rich C-terminal 1

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  CRCT1, cysteine rich C-terminal 1
  
• Synonyms
  C1orf42, NICE-1, NICE1
• Links
  HGNC:29875

  NCBI Gene ID: 54544

  neXtProt AC: NX_Q9UGL9

  UniProt: Q9UGL9

  
  
• Chr Location
  1q21.3; chr1:152514482-152516008 (+)  GRCh38

---

• MGI Vertebrate Homology
  Crct1 stringent orthology
  1 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: CRCT1
• Gene Tree
  Crct1
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  9 phenotype references
  

• All Mutations and Alleles
  6
• Chemically induced (other)
  1
• Gene trapped
  1
• Radiation induced
  1
• Targeted
  3
• Genomic Mutations
  2 involving Crct1
• Find Mice (IMSR)
  10 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  727
• Tissues
  2
• cDNA Data
  30
• Literature Summary
  1

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  34
• RefSeq
  2
• UniProt
  2
• CCDS
  CCDS17578.1

• Ensembl
  ENSMUSG00000027913 (Evidence)
• NCBI Gene
  74175

Representative Sequences			Length	Strain/Species
genomic	74175	NCBI Gene Model | MGI Sequence Detail	1482	C57BL/6J
transcript	NM_028798	RefSeq | MGI Sequence Detail	717	C57BL/6
polypeptide	NP_083074	RefSeq | MGI Sequence Detail	102	C57BL/6

Protein
Information

• UniProt
  2 Sequences
• InterPro Domains
  IPR031698 Cysteine-rich C-terminal protein 1

Molecular
Reagents

• All nucleic 30

  cDNA 30

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:2139602

References

• Summaries
  All 31

  Developmental Gene Expression 1

  Diseases 1

  Gene Ontology 1

  Phenotypes 9
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:302829 Lu J, et al., Mouse models for human hyperuricaemia: a critical review. Nat Rev Rheumatol. 2019 Jul;15(7):413-426

TSS for Crct1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr34341	Chr3:92922986-92923001 (-)	-1 bp