Cep97 MGI Mouse Gene Detail - MGI:1921451

Symbol

Cep97
Name

centrosomal protein 97
Synonyms

2810403B08Rik, 4932439K18Rik, E130116N02Rik, Lrriq2

Feature Type

protein coding gene
IDs

MGI:1921451
NCBI Gene: 74201
Alliance

gene page
Transcription Start Sites

5 TSS

Sequence Map

Chr16:55720251-55755218 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 16, 33.69 cM, cytoband C1.1
Mapping Data

3 experiments

SNPs within 2kb

1255 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1921451	protein coding gene	Chr16:55720250-55755237 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0022882	protein coding gene	Chr16:54992374-55026816 (-)
A/J	MGP_AJ_G0022849	protein coding gene	Chr16:52634370-52669546 (-)
AKR/J	MGP_AKRJ_G0022821	protein coding gene	Chr16:54292267-54331433 (-)
BALB/cJ	MGP_BALBcJ_G0022849	protein coding gene	Chr16:52735272-52770695 (-)
C3H/HeJ	MGP_C3HHeJ_G0022612	protein coding gene	Chr16:54488319-54526465 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0023297	protein coding gene	Chr16:56533391-56575569 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020808	protein coding gene	Chr16:52358230-52393146 (-)
CAST/EiJ	MGP_CASTEiJ_G0022139	protein coding gene	Chr16:54893944-54931990 (-)
CBA/J	MGP_CBAJ_G0022585	protein coding gene	Chr16:58810697-58847464 (-)
DBA/2J	MGP_DBA2J_G0022717	protein coding gene	Chr16:52375731-52414789 (-)
FVB/NJ	MGP_FVBNJ_G0022692	protein coding gene	Chr16:52150679-52184050 (-)
LP/J	MGP_LPJ_G0022784	protein coding gene	Chr16:54810439-54839343 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0022710	protein coding gene	Chr16:59111924-59149815 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0023312	protein coding gene	Chr16:54444788-54479472 (-)
PWK/PhJ	MGP_PWKPhJ_G0021878	protein coding gene	Chr16:52735138-52766388 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0021708	protein coding gene	Chr16:54253734-54290842 (-)
WSB/EiJ	MGP_WSBEiJ_G0022183	protein coding gene	Chr16:54476509-54513697 (-)

Human Ortholog

CEP97, centrosomal protein 97

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CEP97, centrosomal protein 97
Synonyms

2810403B08Rik, LRRIQ2
Links

HGNC:26244

NCBI Gene ID: 79598

neXtProt AC: NX_Q8IW35

UniProt: Q8IW35
Chr Location

3q12.3; chr3:101724534-101770562 (+) GRCh38

MGI Vertebrate Homology

Cep97 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: CEP97
Gene Tree

Cep97

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Phenotype Summary

8 phenotypes from 1 allele in 1 genetic background
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

9
Endonuclease-mediated

1
Gene trapped

5
Targeted

3
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

39 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

13
GO References

8

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

739
Tissues

19
cDNA Data

9
Literature Summary

4

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase cep97

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All Sequences

60
RefSeq

9
UniProt

4
CCDS

CCDS28217.1, CCDS49871.1, CCDS49872.1, CCDS49873.1

Ensembl

ENSMUSG00000022604 (Evidence)
NCBI Gene

74201

			Length	Strain/Species	Flank
genomic	ENSMUSG00000022604	Ensembl Gene Model \| MGI Sequence Detail	34968	C57BL/6J	± kb
transcript	ENSMUST00000023270	Ensembl \| MGI Sequence Detail	7911	Not Applicable
polypeptide	ENSMUSP00000023270	Ensembl \| MGI Sequence Detail	856	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000005359 centrosomal protein of 97 kDa

(term hierarchy)
InterPro Domains

IPR050576 Ciliary and flagellar integrity-associated protein

IPR001611 Leucine-rich repeat

IPR025875 Leucine rich repeat 4

IPR032675 Leucine-rich repeat domain superfamily

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All nucleic 12

cDNA 11

Primer pair 1

Microarray probesets 6

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MGI:1921629, MGI:2443319, MGI:3035362

Summaries

All 45

Developmental Gene Expression 4

Gene Ontology 8

Phenotypes 10
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Cep97:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr141544	Chr16:55755208-55755231 (-)	-2 bp
Tssr141543	Chr16:55755171-55755203 (-)	31 bp
Tssr141542	Chr16:55744349-55744355 (-)	10,866 bp
Tssr141541	Chr16:55744226-55744244 (-)	10,983 bp
Tssr141540	Chr16:55737206-55737214 (-)	18,008 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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