Rbm26 MGI Mouse Gene Detail - MGI:1921463 - RNA binding motif protein 26

Symbol

Rbm26
Name

RNA binding motif protein 26
Synonyms

1700009P03Rik, C230097K14Rik, Pro1777

Feature Type

protein coding gene
IDs

MGI:1921463
NCBI Gene: 74213
Alliance

gene page
Transcription Start Sites

7 TSS

Sequence Map

Chr14:105344187-105414763 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 14, 55.36 cM
Mapping Data

2 experiments

SNPs within 2kb

1468 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1921463	protein coding gene	Chr14:105344187-105418475 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0021636	protein coding gene	Chr14:101682661-101753577 (-)
A/J	MGP_AJ_G0021594	protein coding gene	Chr14:98316938-98392991 (-)
AKR/J	MGP_AKRJ_G0021570	protein coding gene	Chr14:101253769-101326591 (-)
BALB/cJ	MGP_BALBcJ_G0021600	protein coding gene	Chr14:98668908-98739176 (-)
C3H/HeJ	MGP_C3HHeJ_G0021378	protein coding gene	Chr14:101182729-101252730 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0022040	protein coding gene	Chr14:105786970-105859394 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019580	protein coding gene	Chr14:95097489-95168103 (-)
CAST/EiJ	MGP_CASTEiJ_G0020895	protein coding gene	Chr14:98508720-98593311 (-)
CBA/J	MGP_CBAJ_G0021346	protein coding gene	Chr14:109557805-109628559 (-)
DBA/2J	MGP_DBA2J_G0021470	protein coding gene	Chr14:97812004-97884259 (-)
FVB/NJ	MGP_FVBNJ_G0021447	protein coding gene	Chr14:96769501-96842032 (-)
LP/J	MGP_LPJ_G0021538	protein coding gene	Chr14:102498695-102584353 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021474	protein coding gene	Chr14:112423495-112501701 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0022063	protein coding gene	Chr14:100781698-100852931 (-)
PWK/PhJ	MGP_PWKPhJ_G0020638	protein coding gene	Chr14:94779785-94851495 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0020476	protein coding gene	Chr14:96785658-96856968 (-)
WSB/EiJ	MGP_WSBEiJ_G0020948	protein coding gene	Chr14:101418911-101490905 (-)

Human Ortholog

RBM26, RNA binding motif protein 26

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RBM26, RNA binding motif protein 26
Synonyms

ARRS2, C13orf10, PPP1R132, PRO1777, SE70-2, ZC3H17
Links

HGNC:20327

NCBI Gene ID: 64062

neXtProt AC: NX_Q5T8P6

UniProt: Q5T8P6
Chr Location

13q31.1; chr13:79311824-79406477 (-) GRCh38

MGI Vertebrate Homology

Rbm26 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: RBM26
Gene Tree

Rbm26

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
14 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

43
Chemically induced (other)

1
Endonuclease-mediated

1
Gene trapped

37
Radiation induced

1
Targeted

3
Genomic Mutations

2 involving Rbm26
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

58 strains or lines available

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All GO Annotations

4
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

762
Tissues

53
cDNA Data

21
Literature Summary

6

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase rbm26

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All Sequences

112
RefSeq

51
UniProt

5
CCDS

CCDS37003.1, CCDS88725.1

Ensembl

ENSMUSG00000022119 (Evidence)
NCBI Gene

74213

			Length	Strain/Species	Flank
genomic	ENSMUSG00000022119	Ensembl Gene Model \| MGI Sequence Detail	70577	C57BL/6J	± kb
transcript	ENSMUST00000163545	Ensembl \| MGI Sequence Detail	3270	Not Applicable
polypeptide	ENSMUSP00000126414	Ensembl \| MGI Sequence Detail	1009	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000013791 RNA-binding protein 26

(term hierarchy)
InterPro Domains

IPR012677 Nucleotide-binding alpha-beta plait domain superfamily

IPR002483 PWI domain

IPR039511 RBM26-like, RNA recognition motif 2

IPR034859 RBM26, RNA recognition motif 1

IPR035979 RNA-binding domain superfamily

IPR045137 RNA-binding protein 26/27

IPR000504 RNA recognition motif domain

IPR000571 Zinc finger, CCCH-type
GlyGen

Q6NZN0 5 sites, 2 N-linked glycans (2 sites), 1 O-linked glycan (3 sites)

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All nucleic 24

cDNA 21

Primer pair 3

Microarray probesets 9

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MGI:2145642, MGI:2145875, MGI:2441901

Summaries

All 45

Developmental Gene Expression 6

Gene Ontology 2

Phenotypes 14
Earliest

J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Rbm26:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr130156	Chr14:105414716-105414770 (-)	20 bp
Tssr130155	Chr14:105414699-105414713 (-)	57 bp
Tssr130154	Chr14:105414689-105414697 (-)	70 bp
Tssr130153	Chr14:105414308-105414354 (-)	432 bp
Tssr130152	Chr14:105376433-105376438 (-)	38,327 bp
Tssr130151	Chr14:105375811-105375819 (-)	38,948 bp
Tssr130150	Chr14:105354400-105354402 (-)	60,362 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24