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Lrrc74b Gene Detail
Summary
  • Symbol
    Lrrc74b
  • Name
    leucine rich repeat containing 74B
  • Synonyms
    4930451C15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921935
    NCBI Gene: 74685
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:17362329-17379111 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 10.87 cM, cytoband B1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    563 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921935
 protein coding gene Chr16:17362329-17379159 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022584
 protein coding gene Chr16:14701696-14719726 (-)
A/J MGP_AJ_G0022545
 protein coding gene Chr16:13973991-13990773 (-)
AKR/J MGP_AKRJ_G0022522
 protein coding gene Chr16:14520120-14536902 (-)
BALB/cJ MGP_BALBcJ_G0022548
 protein coding gene Chr16:14126522-14143298 (-)
C3H/HeJ MGP_C3HHeJ_G0022315
 protein coding gene Chr16:14672486-14689280 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022999
 protein coding gene Chr16:14935365-14956205 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020519
 protein coding gene Chr16:14041427-14058895 (-)
CAST/EiJ MGP_CASTEiJ_G0021843
 protein coding gene Chr16:14572374-14589857 (-)
CBA/J MGP_CBAJ_G0022286
 protein coding gene Chr16:15610115-15626721 (-)
DBA/2J MGP_DBA2J_G0022416
 protein coding gene Chr16:13892083-13908811 (-)
FVB/NJ MGP_FVBNJ_G0022392
 protein coding gene Chr16:13933721-13950402 (-)
LP/J MGP_LPJ_G0022483
 protein coding gene Chr16:14463669-14480437 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022413
 protein coding gene Chr16:15302466-15319248 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023010
 protein coding gene Chr16:14466322-14483166 (-)
PWK/PhJ MGP_PWKPhJ_G0021586
 protein coding gene Chr16:14144653-14162693 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021414
 protein coding gene Chr16:14441179-14459309 (-)
WSB/EiJ MGP_WSBEiJ_G0021890
 protein coding gene Chr16:14458733-14475845 (-)



Homology
more
  • Human Ortholog
    LRRC74B, leucine rich repeat containing 74B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LRRC74B, leucine rich repeat containing 74B
  • Links
    NCBI Gene ID: 400891
    neXtProt AC: NX_Q6ZQY2
    UniProt: Q6ZQY2

  • Chr Location
    22q11.21; chr22:21045946-21064168 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022759 Ensembl Gene Model | MGI Sequence Detail 16783 C57BL/6J ±  kb
transcript ENSMUST00000100123 Ensembl | MGI Sequence Detail 2231 Not Applicable  
polypeptide ENSMUSP00000097699 Ensembl | MGI Sequence Detail 391 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 2
References
more
  • Summaries
    All 30
    Developmental Gene Expression 1
    Diseases 1
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:348704 Vong KI, et al., Risk of meningomyelocele mediated by the common 22q11.2 deletion. Science. 2024 May 3;384(6695):584-590
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory