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Tmem114 Gene Detail
Summary
  • Symbol
    Tmem114
  • Name
    transmembrane protein 114
  • Synonyms
    4930511J11Rik, Cldn26
  • Feature Type
    protein coding gene
  • IDs
    MGI:1921970
    NCBI Gene: 74720
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:8227140-8243000 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 16, 3.84 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    620 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1921970
protein coding gene Chr16:8227139-8243000 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022491
protein coding gene Chr16:5063552-5079216 (-)
A/J MGP_AJ_G0022453
protein coding gene Chr16:4758142-4776716 (-)
AKR/J MGP_AKRJ_G0022430
protein coding gene Chr16:5019323-5034999 (-)
BALB/cJ MGP_BALBcJ_G0022458
protein coding gene Chr16:4923250-4946821 (-)
C3H/HeJ MGP_C3HHeJ_G0022225
protein coding gene Chr16:5063490-5083441 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022907
protein coding gene Chr16:5198927-5216548 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020428
protein coding gene Chr16:4972132-4985002 (-)
CAST/EiJ MGP_CASTEiJ_G0021751
protein coding gene Chr16:5083073-5117767 (-)
CBA/J MGP_CBAJ_G0022194
protein coding gene Chr16:5402587-5425060 (-)
DBA/2J MGP_DBA2J_G0022325
protein coding gene Chr16:4809483-4825087 (-)
FVB/NJ MGP_FVBNJ_G0022300
protein coding gene Chr16:4797332-4814173 (-)
LP/J MGP_LPJ_G0022393
protein coding gene Chr16:5042827-5064574 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022322
protein coding gene Chr16:5194548-5213576 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022919
protein coding gene Chr16:4985564-5001831 (-)
PWK/PhJ MGP_PWKPhJ_G0021491
protein coding gene Chr16:4966199-5002020 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021322
protein coding gene Chr16:5043893-5063846 (-)
WSB/EiJ MGP_WSBEiJ_G0021800
protein coding gene Chr16:5027336-5046250 (-)



Homology
more
  • Human Ortholog
    TMEM114, transmembrane protein 114
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Mice exhibit normal male fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 74720 NCBI Gene Model | MGI Sequence Detail 15861 C57BL/6J ±  kb
    transcript NM_029070 RefSeq | MGI Sequence Detail 1406 C57BL/6  
    polypeptide Q9D563 UniProt | EBI | MGI Sequence Detail 222 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 7
      Genomic 1
      cDNA 5
      Primer pair 1

      Microarray probesets 2
    References
    more
    • Summaries
      All 27
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 6
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    last database update
    12/10/2024
    MGI 6.24
    The Jackson Laboratory