Eva1b Gene Detail

Summary

• Symbol
  Eva1b
• Name
  eva-1 homolog B
• Synonyms
  2610027C15Rik, Fam176b

• Feature Type
  protein coding gene
• IDs
  MGI:1922063
  NCBI Gene: 230752
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr4:126041537-126043668 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 4, 59.96 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  137 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1922063	protein coding gene	Chr4:126039502-126043668 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0028772	protein coding gene	Chr4:127803004-127805135 (+)
A/J	MGP_AJ_G0028731	protein coding gene	Chr4:122770751-122772882 (+)
AKR/J	MGP_AKRJ_G0028684	protein coding gene	Chr4:126151626-126153757 (+)
BALB/cJ	MGP_BALBcJ_G0028754	protein coding gene	Chr4:123354138-123356269 (+)
C3H/HeJ	MGP_C3HHeJ_G0028468	protein coding gene	Chr4:126203224-126205355 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0029196	protein coding gene	Chr4:132686443-132688574 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0026469	protein coding gene	Chr4:115926952-115929087 (+)
CAST/EiJ	MGP_CASTEiJ_G0027901	protein coding gene	Chr4:124320494-124322626 (+)
CBA/J	MGP_CBAJ_G0028434	protein coding gene	Chr4:135896340-135898471 (+)
DBA/2J	MGP_DBA2J_G0028583	protein coding gene	Chr4:123232676-123234807 (+)
FVB/NJ	MGP_FVBNJ_G0028550	protein coding gene	Chr4:121881849-121883981 (+)
LP/J	MGP_LPJ_G0028684	protein coding gene	Chr4:128089205-128091336 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0028576	protein coding gene	Chr4:140926747-140928879 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0029234	protein coding gene	Chr4:126498490-126500621 (+)
PWK/PhJ	MGP_PWKPhJ_G0027622	protein coding gene	Chr4:119697372-119699503 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0027448	protein coding gene	Chr4:122320548-122322681 (+)
WSB/EiJ	MGP_WSBEiJ_G0027981	protein coding gene	Chr4:126597206-126599337 (+)

Homology

• Human Ortholog
  EVA1B, eva-1 homolog B

• Vertebrate Orthologs
  4

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  EVA1B, eva-1 homolog B
  
• Synonyms
  C1orf78, FAM176B
• Links
  HGNC:25558

  NCBI Gene ID: 55194

  neXtProt AC: NX_Q9NVM1

  UniProt: Q9NVM1

  
  
• Chr Location
  1p34.3; chr1:36322030-36324154 (-)  GRCh38

---

• MGI Vertebrate Homology
  Eva1b stringent orthology
  1 human;1 mouse;1 rat;2 zebrafish
  
• HCOP
  vertebrate homology predictions: EVA1B
• Gene Tree
  Eva1b
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  13 phenotype references
  

• All Mutations and Alleles
  13
• Chemically induced (other)
  2
• Gene trapped
  7
• Radiation induced
  1
• Targeted
  3
• Genomic Mutations
  4 involving Eva1b
• Incidental Mutations
  APF , CvDC
• Find Mice (IMSR)
  12 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  2

Expression

• Assay Results
  789
• Tissues
  18
• cDNA Data
  55
• Literature Summary
  4

Images

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase eva1b

Sequences &
Gene Models

• All Sequences
  47
• RefSeq
  12
• UniProt
  1
• CCDS
  CCDS18643.1

• Ensembl
  ENSMUSG00000050212 (Evidence)
• NCBI Gene
  230752

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000050212	Ensembl Gene Model | MGI Sequence Detail	2132	C57BL/6J
transcript	ENSMUST00000052876	Ensembl | MGI Sequence Detail	1689	Not Applicable
polypeptide	ENSMUSP00000054141	Ensembl | MGI Sequence Detail	164	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000030972 protein eva-1 homolog B
  (term hierarchy)
• InterPro Domains
  IPR039500 EVA1 domain
  IPR052461 EVA1 family of programmed cell death regulators

Molecular
Reagents

• All nucleic 55

  cDNA 55

  
  

  Microarray probesets 3

References

• Summaries
  All 37

  Developmental Gene Expression 4

  Gene Ontology 2

  Phenotypes 13
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034

TSS for Eva1b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr38982	Chr4:126042250-126042320 (+)	748 bp