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Cylc2 Gene Detail
Summary
  • Symbol
    Cylc2
  • Name
    cylicin, basic protein of sperm head cytoskeleton 2
  • Synonyms
    4930488P18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922164
    NCBI Gene: 74914
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:51216678-51250622 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 27.27 cM, cytoband B3
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1096 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922164
 protein coding gene Chr4:51216653-51250625 (+)
129S1/SvImJ MGP_129S1SvImJ_G0028289
 protein coding gene Chr4:49763217-49778078 (+)
A/J MGP_AJ_G0028249
 protein coding gene Chr4:47894188-47906222 (+)
AKR/J MGP_AKRJ_G0028198
 protein coding gene Chr4:49150094-49165369 (+)
BALB/cJ MGP_BALBcJ_G0028268
 protein coding gene Chr4:48024609-48036836 (+)
C3H/HeJ MGP_C3HHeJ_G0027989
 protein coding gene Chr4:49734490-49748962 (+)
C57BL/6NJ MGP_C57BL6NJ_G0028709
 protein coding gene Chr4:51530907-51545236 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026018
 protein coding gene Chr4:44988237-45000212 (+)
CAST/EiJ MGP_CASTEiJ_G0027428
 protein coding gene Chr4:49343420-49357727 (+)
CBA/J MGP_CBAJ_G0027955
 protein coding gene Chr4:53295815-53307925 (+)
DBA/2J MGP_DBA2J_G0028105
 protein coding gene Chr4:47784414-47797265 (+)
FVB/NJ MGP_FVBNJ_G0028072
 protein coding gene Chr4:47068179-47083856 (+)
LP/J MGP_LPJ_G0028204
 protein coding gene Chr4:49869282-49882622 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0028096
 protein coding gene Chr4:56468670-56487563 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0028744
 protein coding gene Chr4:49377765-49390889 (+)
PWK/PhJ MGP_PWKPhJ_G0027153
 protein coding gene Chr4:47828374-47843420 (+)
SPRET/EiJ MGP_SPRETEiJ_G0026981
 protein coding gene Chr4:48753830-48765571 (+)
WSB/EiJ MGP_WSBEiJ_G0027506
 protein coding gene Chr4:49284686-49299422 (+)



Homology
more
  • Human Ortholog
    CYLC2, cylicin 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CYLC2, cylicin 2
  • Links
    NCBI Gene ID: 1539
    neXtProt AC: NX_Q14093
    UniProt: Q14093

  • Chr Location
    9q31.1; chr9:102995311-103018488 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039555 Ensembl Gene Model | MGI Sequence Detail 33945 C57BL/6J ±  kb
transcript ENSMUST00000156384 Ensembl | MGI Sequence Detail 3311 Not Applicable  
polypeptide ENSMUSP00000158665 Ensembl | MGI Sequence Detail 665 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 1
    cDNA 1

    Microarray probesets 2
References
more
  • Summaries
    All 15
    Gene Ontology 1
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:343074 Schneider S, et al., Cylicins are a structural component of the sperm calyx being indispensable for male fertility in mice and human. Elife. 2023 Nov 28;12
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory