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Ct55 Gene Detail
Summary
  • Symbol
    Ct55
  • Name
    cancer/testis antigen 55
  • Synonyms
    4930502E18Rik, Ct55
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922263
    NCBI Gene: 75013
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:52726622-52740532 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 29.99 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    286 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922263
 protein coding gene ChrX:52718510-52740532 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035729
 protein coding gene ChrX:48998057-49011665 (+)
A/J MGP_AJ_G0035711
 protein coding gene ChrX:48891596-48907001 (+)
AKR/J MGP_AKRJ_G0035632
 protein coding gene ChrX:50254179-50270125 (+)
BALB/cJ MGP_BALBcJ_G0035698
 protein coding gene ChrX:48366419-48380276 (+)
C3H/HeJ MGP_C3HHeJ_G0035401
 protein coding gene ChrX:49277768-49291414 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036227
 protein coding gene ChrX:50179660-50193425 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033079
 protein coding gene ChrX:46282164-46296128 (+)
CAST/EiJ MGP_CASTEiJ_G0034694
 protein coding gene ChrX:36560461-36574802 (+)
CBA/J MGP_CBAJ_G0035375
 protein coding gene ChrX:51572428-51587868 (+)
DBA/2J MGP_DBA2J_G0035530
 protein coding gene ChrX:48622789-48636190 (+)
FVB/NJ MGP_FVBNJ_G0035479
 protein coding gene ChrX:48244075-48257364 (+)
LP/J MGP_LPJ_G0035618
 protein coding gene ChrX:49384372-49397770 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035518
 protein coding gene ChrX:53111721-53125390 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036245
 protein coding gene ChrX:48893149-48906749 (+)
PWK/PhJ MGP_PWKPhJ_G0034392
 protein coding gene ChrX:36102159-36116191 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034235
 protein coding gene ChrX:37380550-37394954 (+)
WSB/EiJ MGP_WSBEiJ_G0034837
 protein coding gene ChrX:48458367-48472012 (+)



Homology
more
  • Human Ortholog
    CT55, cancer/testis antigen 55
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CT55, cancer/testis antigen 55
  • Synonyms
    BJHCC20A, CXorf48, SPGFX7
  • Links
    NCBI Gene ID: 54967
    neXtProt AC: NX_Q8WUE5
    UniProt: Q8WUE5

  • Chr Location
    Xq26.3; chrX:135156536-135171827 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human CT55 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    22 phenotypes from 2 alleles in 2 genetic backgrounds
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null allele show reduced susceptibility to weight loss, rectal prolapse and visible tumors in an AOM/DSS model of colitis and tumorogenesis. Mice homozygous for a different null allele show a progressive decline in male fertility along with defects in acrosome development, sperm individualization, excess cytoplasm removal and cumulus-oocyte complex penetration capacity, and an impaired autophagic process during spermatogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 75013 NCBI Gene Model | MGI Sequence Detail 13911 C57BL/6J ±  kb
    transcript NM_029142 RefSeq | MGI Sequence Detail 1203 Not Specified  
    polypeptide Q14BQ3 UniProt | EBI | MGI Sequence Detail 236 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:6370018
    References
    more
    • Summaries
      All 24
      Gene Ontology 2
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    10/29/2024
    MGI 6.24     		The Jackson Laboratory