About   Help   FAQ
Tmbim7 Gene Detail
Summary
  • Symbol
    Tmbim7
  • Name
    transmembrane BAX inhibitor motif containing 7
  • Synonyms
    4930403J02Rik, 4930500J03Rik, 4930511M11Rik, Lfg5, Tmbim1b
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922305
    NCBI Gene: 75010
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:3707004-3729865 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 2.26 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    622 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922305
 protein coding gene Chr5:3701181-3730325 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029261
 protein coding gene Chr5:468710-497541 (+)
A/J MGP_AJ_G0029226
 protein coding gene Chr5:347098-376672 (+)
AKR/J MGP_AKRJ_G0029174
 protein coding gene Chr5:340619-371308 (+)
BALB/cJ MGP_BALBcJ_G0029243
 protein coding gene Chr5:578344-606768 (+)
C3H/HeJ MGP_C3HHeJ_G0028963
 protein coding gene Chr5:516748-545816 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029692
 protein coding gene Chr5:730965-759978 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026935
 protein coding gene Chr5:387431-413485 (+)
CAST/EiJ MGP_CASTEiJ_G0028375
 protein coding gene Chr5:534679-569760 (+)
CBA/J MGP_CBAJ_G0028925
 protein coding gene Chr5:621693-657865 (+)
DBA/2J MGP_DBA2J_G0029075
 protein coding gene Chr5:500432-534541 (+)
FVB/NJ MGP_FVBNJ_G0029037
 protein coding gene Chr5:404270-432982 (+)
LP/J MGP_LPJ_G0029165
 protein coding gene Chr5:504810-535604 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029064
 protein coding gene Chr5:430110-473698 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029723
 protein coding gene Chr5:470054-501192 (+)
PWK/PhJ MGP_PWKPhJ_G0028095
 protein coding gene Chr5:431800-512832 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027930
 protein coding gene Chr5:749914-782575 (+)
WSB/EiJ MGP_WSBEiJ_G0028455
 protein coding gene Chr5:499752-531714 (+)



Homology
more
  • Human Ortholog
    TMBIM7P, transmembrane BAX inhibitor motif containing 7, pseudogene
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMBIM7P, transmembrane BAX inhibitor motif containing 7, pseudogene
  • Links
    NCBI Gene ID: 105375396

  • Chr Location
    7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    714
  • Tissues
    5
  • cDNA Data
    7
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75010 NCBI Gene Model | MGI Sequence Detail 22862 C57BL/6J ±  kb
transcript NM_029141 RefSeq | MGI Sequence Detail 1680 C57BL/6  
polypeptide NP_083417 RefSeq | MGI Sequence Detail 302 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR006214 Bax inhibitor 1-related
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 3
Other
Accession IDs
less
MGI:1922260, MGI:1925403
References
more
  • Summaries
    All 27
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/05/2024
MGI 6.24 		The Jackson Laboratory