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Zbtb49 Gene Detail
Summary
  • Symbol
    Zbtb49
  • Name
    zinc finger and BTB domain containing 49
  • Synonyms
    4930518A03Rik, Zfp509
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922329
    NCBI Gene: 75079
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:38347076-38377798 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 20.25 cM, cytoband B2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1004 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922329
 protein coding gene Chr5:38347076-38377801 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029507
 protein coding gene Chr5:36597040-36627760 (-)
A/J MGP_AJ_G0029473
 protein coding gene Chr5:35368776-35399485 (-)
AKR/J MGP_AKRJ_G0029423
 protein coding gene Chr5:36703988-36734692 (-)
BALB/cJ MGP_BALBcJ_G0029484
 protein coding gene Chr5:35865343-35896052 (-)
C3H/HeJ MGP_C3HHeJ_G0029207
 protein coding gene Chr5:36696063-36726776 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029938
 protein coding gene Chr5:38539255-38569973 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027176
 protein coding gene Chr5:33046384-33076677 (-)
CAST/EiJ MGP_CASTEiJ_G0028615
 protein coding gene Chr5:35857906-35890694 (-)
CBA/J MGP_CBAJ_G0029174
 protein coding gene Chr5:39453524-39484231 (-)
DBA/2J MGP_DBA2J_G0029321
 protein coding gene Chr5:35490999-35522009 (-)
FVB/NJ MGP_FVBNJ_G0029280
 protein coding gene Chr5:34978469-35009191 (-)
LP/J MGP_LPJ_G0029407
 protein coding gene Chr5:37045286-37076166 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029310
 protein coding gene Chr5:40162222-40192944 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029971
 protein coding gene Chr5:36192539-36223265 (-)
PWK/PhJ MGP_PWKPhJ_G0028339
 protein coding gene Chr5:34659449-34691152 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028173
 protein coding gene Chr5:35643656-35674383 (-)
WSB/EiJ MGP_WSBEiJ_G0028696
 protein coding gene Chr5:36269652-36304077 (-)



Homology
more
  • Human Ortholog
    ZBTB49, zinc finger and BTB domain containing 49
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZBTB49, zinc finger and BTB domain containing 49
  • Synonyms
    ZNF509
  • Links
    NCBI Gene ID: 166793
    neXtProt AC: NX_Q6ZSB9
    UniProt: Q6ZSB9

  • Chr Location
    4p16.3; chr4:4290251-4321786 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    25 phenotype references
  • All Mutations and Alleles
    12
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Gene trapped
    3
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    6 involving Zbtb49
  • Incidental Mutations
    Mutagenetix , APF , CvDC
  • Find Mice (IMSR)
    29 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    29
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    760
  • Tissues
    33
  • cDNA Data
    23
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 75079 NCBI Gene Model | MGI Sequence Detail 30723 C57BL/6J ±  kb
transcript NR_174702 RefSeq | MGI Sequence Detail 3050 C57BL/6  
polypeptide Q8BXX2 UniProt | EBI | MGI Sequence Detail 756 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 25
    cDNA 25

    Microarray probesets 4
References
more
  • Summaries
    All 54
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 5
    Phenotypes 25
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:308922 Medeiros de Araujo JA, et al., ZBTB20 is crucial for the specification of a subset of callosal projection neurons and astrocytes in the mammalian neocortex. Development. 2021 Aug 15;148(16):dev196642
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory