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Ankrd53 Gene Detail
Summary
  • Symbol
    Ankrd53
  • Name
    ankyrin repeat domain 53
  • Synonyms
    4930564N15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922555
    NCBI Gene: 75305
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:83739626-83745308 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 35.94 cM, cytoband D1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    232 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922555
 protein coding gene Chr6:83739626-83745336 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030939
 protein coding gene Chr6:84796915-84802597 (+)
A/J MGP_AJ_G0030908
 protein coding gene Chr6:81567413-81573095 (+)
AKR/J MGP_AKRJ_G0030836
 protein coding gene Chr6:83928616-83934298 (+)
BALB/cJ MGP_BALBcJ_G0030918
 protein coding gene Chr6:81595412-81601094 (+)
C3H/HeJ MGP_C3HHeJ_G0030792
 protein coding gene Chr6:100474419-100480101 (-)
C57BL/6NJ MGP_C57BL6NJ_G0031378
 protein coding gene Chr6:87143075-87148757 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028564
 protein coding gene Chr6:79930347-79936875 (+)
CAST/EiJ MGP_CASTEiJ_G0030027
 protein coding gene Chr6:83954587-83960273 (+)
CBA/J MGP_CBAJ_G0030605
 protein coding gene Chr6:90560768-90566450 (+)
DBA/2J MGP_DBA2J_G0030758
 protein coding gene Chr6:80880454-80886136 (+)
FVB/NJ MGP_FVBNJ_G0030711
 protein coding gene Chr6:80092095-80097777 (+)
LP/J MGP_LPJ_G0030837
 protein coding gene Chr6:84798763-84804445 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030747
 protein coding gene Chr6:94826559-94832241 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031402
 protein coding gene Chr6:83758245-83763927 (+)
PWK/PhJ MGP_PWKPhJ_G0029742
 protein coding gene Chr6:79797628-79803310 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029570
 protein coding gene Chr6:82580494-82586596 (+)
WSB/EiJ MGP_WSBEiJ_G0030108
 protein coding gene Chr6:84175647-84181328 (+)



Homology
more
  • Human Ortholog
    ANKRD53, ankyrin repeat domain 53
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANKRD53, ankyrin repeat domain 53
  • Links
    NCBI Gene ID: 79998
    neXtProt AC: NX_Q8N9V6
    UniProt: Q8N9V6

  • Chr Location
    2p13.3; chr2:70978380-70985499 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    707
  • Tissues
    1
  • cDNA Data
    5
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000014747 Ensembl Gene Model | MGI Sequence Detail 5683 C57BL/6J ±  kb
transcript ENSMUST00000014891 Ensembl | MGI Sequence Detail 1739 Not Applicable  
polypeptide ENSMUSP00000014891 Ensembl | MGI Sequence Detail 497 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 7
    Genomic 2
    cDNA 5

    Microarray probesets 1
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory