Taf1d MGI Mouse Gene Detail - MGI:1922566 - TATA-box binding protein associated factor, RNA polymerase I, D

Symbol

Taf1d
Name

TATA-box binding protein associated factor, RNA polymerase I, D
Synonyms

2810003M17Rik, 4930553M18Rik, 5930426I11Rik, Josd3, TAF(I)41, TAFI41

Feature Type

protein coding gene
IDs

MGI:1922566
NCBI Gene: 75316
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr9:15217510-15228287 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 9, 4.78 cM, cytoband A3
Mapping Data

1 experiment

SNPs within 2kb

310 from dbSNP Build 142
Strain Annotations

17

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1922566	protein coding gene	Chr9:15217485-15228293 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0034364	protein coding gene	Chr9:12289510-12295400 (+)
A/J	MGP_AJ_G0034342	protein coding gene	Chr9:12222035-12227925 (+)
AKR/J	MGP_AKRJ_G0034270	protein coding gene	Chr9:12247508-12253398 (+)
BALB/cJ	MGP_BALBcJ_G0034336	protein coding gene	Chr9:11993553-11999443 (+)
C3H/HeJ	MGP_C3HHeJ_G0034047	protein coding gene	Chr9:12558216-12564106 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0034858	protein coding gene	Chr9:12688407-12695355 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0031796	protein coding gene	Chr9:11492357-11498615 (+)
CAST/EiJ	MGP_CASTEiJ_G0033374	protein coding gene	Chr9:12402436-12409019 (+)
CBA/J	MGP_CBAJ_G0034020	protein coding gene	Chr9:13280181-13286081 (+)
DBA/2J	MGP_DBA2J_G0034177	protein coding gene	Chr9:12081736-12087626 (+)
FVB/NJ	MGP_FVBNJ_G0034122	protein coding gene	Chr9:11675595-11681470 (+)
LP/J	MGP_LPJ_G0034263	protein coding gene	Chr9:12390867-12396773 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0034166	protein coding gene	Chr9:14289999-14295888 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0034877	protein coding gene	Chr9:12276478-12282352 (+)
PWK/PhJ	MGP_PWKPhJ_G0033080	protein coding gene	Chr9:12161505-12167503 (+)
SPRET/EiJ	no annotation
WSB/EiJ	MGP_WSBEiJ_G0033490	protein coding gene	Chr9:12114540-12121160 (+)

Human Ortholog

TAF1D, TATA-box binding protein associated factor, RNA polymerase I subunit D

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

TAF1D, TATA-box binding protein associated factor, RNA polymerase I subunit D
Synonyms

JOSD3, RAFI41, TAF(I)41, TAFI41
Links

HGNC:28759

NCBI Gene ID: 79101

neXtProt AC: NX_Q9H5J8

UniProt: Q9H5J8
Chr Location

11q21; chr11:93729948-93784391 (-) GRCh38

MGI Vertebrate Homology

Taf1d stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: TAF1D
Gene Tree

Taf1d

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Phenotype Summary

4 phenotypes from 1 allele in 2 genetic backgrounds
1 images
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

96
Endonuclease-mediated

1
Gene trapped

95
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

45 strains or lines available

Mice homozygous for a knock-out allele show embryonic lethality before implantation. In vitro, embryos fail to hatch from the zona pellucida and die after 3 days in culture, never forming outgrowths.

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All GO Annotations

10
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

811
Tissues

102
cDNA Data

24
Literature Summary

2

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

GEISHA TAF1D

Xenbase taf1d

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All Sequences

102
RefSeq

24
UniProt

6
CCDS

CCDS22836.1, CCDS52726.1

Ensembl

ENSMUSG00000031939 (Evidence)
NCBI Gene

75316

			Length	Strain/Species	Flank
genomic	ENSMUSG00000031939	Ensembl Gene Model \| MGI Sequence Detail	10778	C57BL/6J	± kb
transcript	ENSMUST00000034415	Ensembl \| MGI Sequence Detail	1148	Not Applicable
polypeptide	ENSMUSP00000034415	Ensembl \| MGI Sequence Detail	322	Not Applicable

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UniProt

6 Sequences
Protein Ontology

PR:000016023 TATA box-binding protein-associated factor RNA polymerase I subunit D

(term hierarchy)
InterPro Domains

IPR027976 TATA box-binding protein-associated factor 1D

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All nucleic 30

cDNA 26

Primer pair 3

Other 1

Microarray probesets 12

Summaries

All 40

Developmental Gene Expression 2

Gene Ontology 4

Phenotypes 10
Earliest

J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Taf1d:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr83860	Chr9:15217508-15217515 (+)	2 bp
Tssr83861	Chr9:15217517-15217536 (+)	17 bp
Tssr83862	Chr9:15217548-15217564 (+)	46 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24