Cimip2c MGI Mouse Gene Detail - MGI:1922684 - ciliary microtubule inner protein 2C

Symbol

Cimip2c
Name

ciliary microtubule inner protein 2C
Synonyms

1700001C02Rik, 1700047H18Rik, Fam166c

Feature Type

protein coding gene
IDs

MGI:1922684
NCBI Gene: 75434
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr5:30623395-30641433 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 16.57 cM, cytoband B1
Mapping Data

2 experiments

SNPs within 2kb

566 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1922684	protein coding gene	Chr5:30623391-30641433 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0029390	protein coding gene	Chr5:28406287-28424169 (+)
A/J	MGP_AJ_G0029356	protein coding gene	Chr5:27477267-27495461 (+)
AKR/J	MGP_AKRJ_G0029307	protein coding gene	Chr5:28618029-28637706 (+)
BALB/cJ	MGP_BALBcJ_G0029367	protein coding gene	Chr5:28004143-28022167 (+)
C3H/HeJ	MGP_C3HHeJ_G0029088	protein coding gene	Chr5:28614136-28633461 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0029820	protein coding gene	Chr5:30140425-30159936 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027058	protein coding gene	Chr5:24970337-24987804 (+)
CAST/EiJ	MGP_CASTEiJ_G0028499	protein coding gene	Chr5:27710199-27728206 (+)
CBA/J	MGP_CBAJ_G0029056	protein coding gene	Chr5:30736964-30757399 (+)
DBA/2J	MGP_DBA2J_G0029205	protein coding gene	Chr5:27665792-27684208 (+)
FVB/NJ	MGP_FVBNJ_G0029163	protein coding gene	Chr5:27077040-27095344 (+)
LP/J	MGP_LPJ_G0029290	protein coding gene	Chr5:28863671-28883131 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0029192	protein coding gene	Chr5:31638205-31657539 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0029854	protein coding gene	Chr5:28121882-28141216 (+)
PWK/PhJ	MGP_PWKPhJ_G0028223	protein coding gene	Chr5:26780106-26798182 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0028054	protein coding gene	Chr5:27463351-27483467 (+)
WSB/EiJ	MGP_WSBEiJ_G0028579	protein coding gene	Chr5:28198906-28216957 (+)

Human Ortholog

CIMIP2C, ciliary microtubule inner protein 2C

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

CIMIP2C, ciliary microtubule inner protein 2C
Synonyms

C2orf70, FAM166C
Links

HGNC:27938

NCBI Gene ID: 339778

neXtProt AC: NX_A6NJV1

UniProt: A6NJV1
Chr Location

2p23.3; chr2:26562585-26579532 (+) GRCh38

MGI Vertebrate Homology

Cimip2c stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: CIMIP2C
Gene Tree

Cimip2c

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References

1 with disease annotations

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
29 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

10
Chemically induced (other)

2
Endonuclease-mediated

1
Gene trapped

2
Radiation induced

3
Spontaneous

1
Targeted

1
Genomic Mutations

6 involving Cimip2c
Find Mice (IMSR)

14 strains or lines available

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All GO Annotations

5
GO References

4

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

747
Tissues

32
cDNA Data

11
Literature Summary

4

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase cimip2c

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All Sequences

44
RefSeq

8
UniProt

3
CCDS

CCDS19158.1

Ensembl

ENSMUSG00000029182 (Evidence)
NCBI Gene

75434

			Length	Strain/Species	Flank
genomic	75434	NCBI Gene Model \| MGI Sequence Detail	18039	C57BL/6J	± kb
transcript	NM_001417888	RefSeq \| MGI Sequence Detail	863	C57BL/6
polypeptide	Q9DAS2	UniProt \| EBI \| MGI Sequence Detail	200	Not Applicable

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UniProt

3 Sequences
Protein Ontology

PR:000059704 ciliary microtubule inner protein 2C

(term hierarchy)
PDB

8I7O, 8I7R, 8IYJ
InterPro Domains

IPR018902 Ciliary microtubule inner protein 2A-C-like

IPR052329 Ciliary Microtubule Inner Protein 2C

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All nucleic 12

cDNA 11

Primer pair 1

Microarray probesets 4

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MGI:1920619, MGI:6369069, MGI:7470737

Summaries

All 57

Developmental Gene Expression 4

Diseases 1

Gene Ontology 4

Phenotypes 29
Earliest

J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Cimip2c:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr45583	Chr5:30623388-30623436 (+)	17 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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