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Gpx6 Gene Detail
Summary
  • Symbol
    Gpx6
  • Name
    glutathione peroxidase 6
  • Synonyms
    1700020G18Rik, olfactory
  • Feature Type
    protein coding gene
  • IDs
    MGI:1922762
    NCBI Gene: 75512
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:21496295-21503794 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 7.74 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    341 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1922762
 protein coding gene Chr13:21479635-21503795 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020271
 protein coding gene Chr13:18564571-18571905 (+)
A/J MGP_AJ_G0020227
 protein coding gene Chr13:18163403-18170771 (+)
AKR/J MGP_AKRJ_G0020203
 protein coding gene Chr13:18469217-18477349 (+)
BALB/cJ MGP_BALBcJ_G0020215
 protein coding gene Chr13:18214675-18222070 (+)
C3H/HeJ MGP_C3HHeJ_G0020016
 protein coding gene Chr13:18560674-18567951 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020659
 protein coding gene Chr13:19219959-19227893 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018266
 protein coding gene Chr13:16531410-16538964 (+)
CAST/EiJ MGP_CASTEiJ_G0019553
 protein coding gene Chr13:18364925-18373164 (+)
CBA/J MGP_CBAJ_G0019980
 protein coding gene Chr13:19886154-19893545 (+)
DBA/2J MGP_DBA2J_G0020101
 protein coding gene Chr13:17799751-17807198 (+)
FVB/NJ MGP_FVBNJ_G0020083
 protein coding gene Chr13:17467852-17475132 (+)
LP/J MGP_LPJ_G0020172
 protein coding gene Chr13:18808281-18815899 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020121
 protein coding gene Chr13:20285128-20293458 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020687
 protein coding gene Chr13:18287096-18294707 (+)
PWK/PhJ MGP_PWKPhJ_G0019316
 protein coding gene Chr13:17848891-17856810 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019122
 protein coding gene Chr13:17297587-17304929 (+)
WSB/EiJ MGP_WSBEiJ_G0019610
 protein coding gene Chr13:18364975-18372670 (+)



Homology
more
  • Human Ortholog
    GPX6, glutathione peroxidase 6
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GPX6, glutathione peroxidase 6
  • Synonyms
    dJ1186N24, dJ1186N24.1, GPX5p, GPx-6, GPXP3, GSHPx-6
  • Links
    NCBI Gene ID: 257202
    neXtProt AC: NX_P59796
    UniProt: P59796

  • Chr Location
    6p22.1
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    843
  • Tissues
    137
  • cDNA Data
    18
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000004341 Ensembl Gene Model | MGI Sequence Detail 7500 C57BL/6J ±  kb
transcript ENSMUST00000004453 Ensembl | MGI Sequence Detail 1340 Not Applicable  
polypeptide ENSMUSP00000004453 Ensembl | MGI Sequence Detail 221 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 20
    cDNA 18
    Primer pair 2

    Microarray probesets 2
References
more
  • Summaries
    All 46
    Developmental Gene Expression 4
    Gene Ontology 6
    Phenotypes 18
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory