Sgf29 MGI Mouse Gene Detail - MGI:1922815 - SAGA complex associated factor 29

Symbol

Sgf29
Name

SAGA complex associated factor 29
Synonyms

1700023O11Rik, Ccdc101

Feature Type

protein coding gene
IDs

MGI:1922815
NCBI Gene: 75565
Alliance

gene page
Transcription Start Sites

7 TSS

Sequence Map

Chr7:126248481-126272097 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 69.23 cM, cytoband F4
Mapping Data

2 experiments

SNPs within 2kb

557 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1922815	protein coding gene	Chr7:126247558-126272097 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0032990	protein coding gene	Chr7:130932951-130956493 (+)
A/J	MGP_AJ_G0032973	protein coding gene	Chr7:127469791-127491713 (+)
AKR/J	MGP_AKRJ_G0032905	protein coding gene	Chr7:130697825-130724713 (+)
BALB/cJ	MGP_BALBcJ_G0032978	protein coding gene	Chr7:127128817-127152459 (+)
C3H/HeJ	MGP_C3HHeJ_G0032688	protein coding gene	Chr7:130633179-130658155 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0033484	protein coding gene	Chr7:136025155-136058713 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0030456	protein coding gene	Chr7:128657762-128681199 (+)
CAST/EiJ	MGP_CASTEiJ_G0032016	protein coding gene	Chr7:122417731-122454279 (+)
CBA/J	MGP_CBAJ_G0032661	protein coding gene	Chr7:140604048-140633744 (+)
DBA/2J	MGP_DBA2J_G0032813	protein coding gene	Chr7:125446226-125471249 (+)
FVB/NJ	MGP_FVBNJ_G0032766	protein coding gene	Chr7:125295946-125319607 (+)
LP/J	MGP_LPJ_G0032907	protein coding gene	Chr7:132402263-132425658 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0032798	protein coding gene	Chr7:141789216-141822185 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0033503	protein coding gene	Chr7:129708710-129735149 (+)
PWK/PhJ	MGP_PWKPhJ_G0031724	protein coding gene	Chr7:118436100-118459966 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0031570	protein coding gene	Chr7:116543298-116571064 (+)
WSB/EiJ	MGP_WSBEiJ_G0032129	protein coding gene	Chr7:130685967-130709298 (+)

Human Ortholog

SGF29, SAGA complex associated factor 29

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SGF29, SAGA complex associated factor 29
Synonyms

CCDC101, STAF36, TDRD29
Links

HGNC:25156

NCBI Gene ID: 112869

neXtProt AC: NX_Q96ES7

UniProt: Q96ES7
Chr Location

16p11.2; chr16:28553915-28591790 (+) GRCh38

MGI Vertebrate Homology

Sgf29 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: SGF29
Gene Tree

Sgf29

Diseases

1 with human SGF29 associations

				Human Disease	Mouse Models
				diabetic retinopathy IDs diabetic retinopathy DOID:8947 ICD9CM:362.0 MESH:D003930 NCI:C34538 UMLS_CUI:C0011884

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

24
Endonuclease-mediated

1
Gene trapped

20
Targeted

3
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

35 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

41
GO References

14

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

711
Tissues

5
cDNA Data

50
Literature Summary

1

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

GEISHA SGF29

Xenbase sgf29

ZFIN sgf29

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All Sequences

51
RefSeq

4
UniProt

5
CCDS

CCDS21837.1

Ensembl

ENSMUSG00000030714 (Evidence)
NCBI Gene

75565

			Length	Strain/Species	Flank
genomic	ENSMUSG00000030714	Ensembl Gene Model \| MGI Sequence Detail	23617	C57BL/6J	± kb
transcript	ENSMUST00000032956	Ensembl \| MGI Sequence Detail	1312	Not Applicable
polypeptide	ENSMUSP00000032956	Ensembl \| MGI Sequence Detail	293	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000005099 SAGA-associated factor 29

(term hierarchy)
InterPro Domains

IPR037802 SAGA-associated factor 29

IPR047288 SAGA-associated factor 29, first Tudor domain

IPR047287 SAGA-associated factor 29, second Tudor domain

IPR010750 SGF29 tudor-like domain

IPR011990 Tetratricopeptide-like helical domain superfamily

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All nucleic 50

cDNA 50

Microarray probesets 5

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MGI:1915373

Summaries

All 45

Developmental Gene Expression 1

Gene Ontology 14

Phenotypes 10
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Sgf29:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr69048	Chr7:126248469-126248516 (+)	12 bp
Tssr69049	Chr7:126248522-126248539 (+)	50 bp
Tssr69050	Chr7:126248549-126248560 (+)	74 bp
Tssr69051	Chr7:126248582-126248604 (+)	112 bp
Tssr69052	Chr7:126255196-126255216 (+)	6,725 bp
Tssr69053	Chr7:126263088-126263096 (+)	14,611 bp
Tssr69054	Chr7:126263117-126263143 (+)	14,649 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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