Bicdl1 MGI Mouse Gene Detail - MGI:1922915 - BICD family like cargo adaptor 1

Symbol

Bicdl1
Name

BICD family like cargo adaptor 1
Synonyms

2210403N09Rik, BICDR-1, Ccdc64

Feature Type

protein coding gene
IDs

MGI:1922915
NCBI Gene: 75665
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr5:115786234-115869680 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 56.10 cM
Mapping Data

1 experiment

SNPs within 2kb

2044 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1922915	protein coding gene	Chr5:115786233-115869824 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0029976	protein coding gene	Chr5:118556231-118643165 (-)
A/J	MGP_AJ_G0029940	protein coding gene	Chr5:113826826-113910022 (-)
AKR/J	MGP_AKRJ_G0029879	protein coding gene	Chr5:117473376-117556743 (-)
BALB/cJ	MGP_BALBcJ_G0029951	protein coding gene	Chr5:115225935-115310705 (-)
C3H/HeJ	MGP_C3HHeJ_G0029671	protein coding gene	Chr5:117988954-118076737 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0030406	protein coding gene	Chr5:123108084-123204493 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027308	protein coding gene	Chr5:68061949-108682741 (-)
CAST/EiJ	MGP_CASTEiJ_G0029080	protein coding gene	Chr5:116939144-117030296 (-)
CBA/J	MGP_CBAJ_G0029639	protein coding gene	Chr5:127835401-127924374 (-)
DBA/2J	MGP_DBA2J_G0029789	protein coding gene	Chr5:113916131-114000278 (-)
FVB/NJ	MGP_FVBNJ_G0029745	protein coding gene	Chr5:112734793-112818066 (-)
LP/J	MGP_LPJ_G0029877	protein coding gene	Chr5:119116492-119202596 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0029776	protein coding gene	Chr5:132138163-132228104 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0030447	protein coding gene	Chr5:116954209-117039950 (-)
PWK/PhJ	MGP_PWKPhJ_G0028793	protein coding gene	Chr5:112562143-112649130 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0028631	protein coding gene	Chr5:114495228-114587098 (-)
WSB/EiJ	MGP_WSBEiJ_G0029155	protein coding gene	Chr5:117547915-117634391 (-)

Human Ortholog

BICDL1, BICD family like cargo adaptor 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

BICDL1, BICD family like cargo adaptor 1
Synonyms

BICDR-1, BICDR1, CCDC64, CCDC64A, H_267D11.1
Links

HGNC:28095

NCBI Gene ID: 92558

neXtProt AC: NX_Q6ZP65

UniProt: Q6ZP65
Chr Location

12q24.23; chr12:119989236-120094495 (+) GRCh38

MGI Vertebrate Homology

Bicdl1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: BICDL1
Gene Tree

Bicdl1

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Phenotype Summary

8 phenotypes from 1 allele in 1 genetic background
14 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

7
Chemically induced (other)

1
Endonuclease-mediated

1
Radiation induced

1
Targeted

4
Genomic Mutations

2 involving Bicdl1
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

22 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

11
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

768
Tissues

45
cDNA Data

47
Literature Summary

3

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase bicdl1

ZFIN bicdl1

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All Sequences

70
RefSeq

15
UniProt

6
CCDS

CCDS39230.1

Ensembl

ENSMUSG00000041609 (Evidence)
NCBI Gene

75665

			Length	Strain/Species	Flank
genomic	ENSMUSG00000041609	Ensembl Gene Model \| MGI Sequence Detail	83447	C57BL/6J	± kb
transcript	ENSMUST00000055408	Ensembl \| MGI Sequence Detail	3026	Not Applicable
polypeptide	ENSMUSP00000053547	Ensembl \| MGI Sequence Detail	577	Not Applicable

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UniProt

6 Sequences
Protein Ontology

PR:000032166 BICD family-like cargo adapter 1

(term hierarchy)
PDB

6F1T, 6F1U, 6ZNM, 7Z8F, 7Z8I, 7Z8J, 7Z8K, 7Z8M
InterPro Domains

IPR051149 Spindly/BICDR Dynein Motor Adapter

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All nucleic 52

Genomic 2

cDNA 47

Primer pair 3

Microarray probesets 3

Summaries

All 39

Developmental Gene Expression 3

Gene Ontology 3

Phenotypes 14
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Bicdl1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr52827	Chr5:115870540-115870555 (-)	-868 bp
Tssr52826	Chr5:115870316-115870342 (-)	-649 bp
Tssr52825	Chr5:115870270-115870315 (-)	-613 bp
Tssr52824	Chr5:115791033-115791051 (-)	78,638 bp
Tssr52823	Chr5:115791012-115791025 (-)	78,661 bp
Tssr52822	Chr5:115790885-115790888 (-)	78,793 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24