Rasl10a MGI Mouse Gene Detail - MGI:1922918 - RAS-like, family 10, member A

Symbol

Rasl10a
Name

RAS-like, family 10, member A
Synonyms

2210403B10Rik

Feature Type

protein coding gene
IDs

MGI:1922918
NCBI Gene: 75668
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr11:5008128-5010385 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 11, 3.21 cM
Mapping Data

2 experiments

SNPs within 2kb

78 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1922918	protein coding gene	Chr11:5008128-5010385 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0017995	protein coding gene	Chr11:2078239-2080478 (+)
A/J	MGP_AJ_G0017968	protein coding gene	Chr11:2016210-2018455 (+)
AKR/J	MGP_AKRJ_G0017932	protein coding gene	Chr11:2111113-2113344 (+)
BALB/cJ	MGP_BALBcJ_G0017936	protein coding gene	Chr11:1988171-1990398 (+)
C3H/HeJ	MGP_C3HHeJ_G0017749	protein coding gene	Chr11:2000231-2003372 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0018388	protein coding gene	Chr11:2147869-2152040 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016046	protein coding gene	Chr11:1908865-1910886 (+)
CAST/EiJ	MGP_CASTEiJ_G0017311	protein coding gene	Chr11:1977160-1979321 (+)
CBA/J	MGP_CBAJ_G0017724	protein coding gene	Chr11:2441759-2446001 (+)
DBA/2J	MGP_DBA2J_G0017834	protein coding gene	Chr11:1916237-1918482 (+)
FVB/NJ	MGP_FVBNJ_G0017826	protein coding gene	Chr11:1954262-1956493 (+)
LP/J	MGP_LPJ_G0017905	protein coding gene	Chr11:2153595-2155834 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0017852	protein coding gene	Chr11:2075425-2077670 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0018428	protein coding gene	Chr11:2111717-2113948 (+)
PWK/PhJ	MGP_PWKPhJ_G0017091	protein coding gene	Chr11:1932664-1935008 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0016888	protein coding gene	Chr11:2102682-2105760 (+)
WSB/EiJ	MGP_WSBEiJ_G0017365	protein coding gene	Chr11:1982546-1984783 (+)

Human Ortholog

RASL10A, RAS like family 10 member A

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

RASL10A, RAS like family 10 member A
Synonyms

RRP22
Links

HGNC:16954

NCBI Gene ID: 10633

neXtProt AC: NX_Q92737

UniProt: Q92737
Chr Location

22q12.2; chr22:29312933-29319859 (-) GRCh38

MGI Vertebrate Homology

Rasl10a stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: RASL10A
Gene Tree

Rasl10a

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Phenotype Summary

1 phenotype reference

All Mutations and Alleles

1
Targeted

1
Find Mice (IMSR)

14 strains or lines available

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All GO Annotations

4
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

4

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase rasl10a

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All Sequences

36
RefSeq

4
UniProt

2
CCDS

CCDS24394.1

Ensembl

ENSMUSG00000034209 (Evidence)
NCBI Gene

75668

			Length	Strain/Species	Flank
genomic	75668	NCBI Gene Model \| MGI Sequence Detail	2258	C57BL/6J	± kb
transcript	NM_001363179	RefSeq \| MGI Sequence Detail	1202	C57BL/6
polypeptide	Q8K5A4	UniProt \| EBI \| MGI Sequence Detail	203	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000030672 Ras-like protein family member 10A

(term hierarchy)
EC

3.6.5.2
InterPro Domains

IPR027417 P-loop containing nucleoside triphosphate hydrolase

IPR052661 Ras-like GTPase Regulators

IPR001806 Small GTPase

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All nucleic 6

Genomic 1

cDNA 5

Microarray probesets 3

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MGI:2144314

Summaries

All 23

Gene Ontology 3

Phenotypes 1
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:162220 Magdaleno S, et al., BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86

TSS for Rasl10a:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr100162	Chr11:5008021-5008045 (+)	-95 bp
Tssr100163	Chr11:5008111-5008147 (+)	1 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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