Idnk MGI Mouse Gene Detail - MGI:1922981 - idnK gluconokinase homolog (E. coli)

Symbol

Idnk
Name

idnK gluconokinase homolog (E. coli)
Synonyms

5133401N09Rik

Feature Type

protein coding gene
IDs

MGI:1922981
NCBI Gene: 75731
Alliance

gene page
Transcription Start Sites

2 TSS

Sequence Map

Chr13:58305463-58312507 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 13, 30.95 cM
Mapping Data

1 experiment

SNPs within 2kb

309 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1922981	protein coding gene	Chr13:58305076-58315358 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0020628	protein coding gene	Chr13:57784668-57790779 (+)
A/J	MGP_AJ_G0020582	protein coding gene	Chr13:55639075-55646050 (+)
AKR/J	MGP_AKRJ_G0020560	protein coding gene	Chr13:57299373-57306616 (+)
BALB/cJ	MGP_BALBcJ_G0020578	protein coding gene	Chr13:55889122-55896407 (+)
C3H/HeJ	MGP_C3HHeJ_G0020377	protein coding gene	Chr13:57105805-57114546 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0021012	protein coding gene	Chr13:59562337-59569580 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0018594	protein coding gene	Chr13:53542023-53549298 (+)
CAST/EiJ	MGP_CASTEiJ_G0019891	protein coding gene	Chr13:57227317-57233496 (+)
CBA/J	MGP_CBAJ_G0020337	protein coding gene	Chr13:61810519-61818265 (+)
DBA/2J	MGP_DBA2J_G0020460	protein coding gene	Chr13:55180042-55187427 (+)
FVB/NJ	MGP_FVBNJ_G0020439	protein coding gene	Chr13:54668426-54675393 (+)
LP/J	MGP_LPJ_G0020536	protein coding gene	Chr13:58056129-58062095 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0020468	protein coding gene	Chr13:61176970-61184343 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021055	protein coding gene	Chr13:56898572-56904701 (+)
PWK/PhJ	MGP_PWKPhJ_G0019647	protein coding gene	Chr13:55181860-55190181 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0019474	protein coding gene	Chr13:55809871-55816850 (+)
WSB/EiJ	MGP_WSBEiJ_G0019953	protein coding gene	Chr13:57339060-57345107 (+)

Human Ortholog

IDNK, IDNK gluconokinase

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

IDNK, IDNK gluconokinase
Synonyms

bA522I20.2, C9orf103, hGntK
Links

HGNC:31367

NCBI Gene ID: 414328

neXtProt AC: NX_Q5T6J7

UniProt: Q5T6J7
Chr Location

9q21.32

MGI Vertebrate Homology

Idnk stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: IDNK
Gene Tree

Idnk

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
7 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

8
Chemically induced (other)

1
Endonuclease-mediated

2
Gene trapped

2
Targeted

3
Genomic Mutations

1 involving Idnk
Find Mice (IMSR)

10 strains or lines available

Female mice homozygous for a targeted mutation exhibit impaired learning/memory during trace aversive conditioning, and both males and females show decreased tear production.

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All GO Annotations

6
GO References

5

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

765
Tissues

8
cDNA Data

32
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase idnk

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All Sequences

52
RefSeq

6
UniProt

4
CCDS

CCDS36682.1, CCDS36683.1

Ensembl

ENSMUSG00000050002 (Evidence)
NCBI Gene

75731

			Length	Strain/Species	Flank
genomic	ENSMUSG00000050002	Ensembl Gene Model \| MGI Sequence Detail	7045	C57BL/6J	± kb
transcript	ENSMUST00000051490	Ensembl \| MGI Sequence Detail	764	Not Applicable
polypeptide	ENSMUSP00000060218	Ensembl \| MGI Sequence Detail	184	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000029112 probable gluconokinase

(term hierarchy)
EC

2.7.1.12
InterPro Domains

IPR006001 Carbohydrate kinase, thermoresistant glucokinase

IPR027417 P-loop containing nucleoside triphosphate hydrolase

IPR031322 Shikimate kinase/gluconokinase

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All nucleic 32

cDNA 32

Microarray probesets 6

Summaries

All 29

Developmental Gene Expression 1

Gene Ontology 5

Phenotypes 7
Earliest

J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
Latest

J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Idnk:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr120066	Chr13:58305441-58305448 (+)	-18 bp
Tssr120067	Chr13:58305456-58305503 (+)	17 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24