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Tmem125 Gene Detail
Summary
  • Symbol
    Tmem125
  • Name
    transmembrane protein 125
  • Synonyms
    6330530A05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923409
    NCBI Gene: 230678
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:118398138-118401241 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 54.81 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    186 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923409
 protein coding gene Chr4:118398138-118402110 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028672
 protein coding gene Chr4:119602631-119605734 (-)
A/J MGP_AJ_G0028633
 protein coding gene Chr4:114958407-114961510 (-)
AKR/J MGP_AKRJ_G0028583
 protein coding gene Chr4:117492726-117495829 (-)
BALB/cJ MGP_BALBcJ_G0028654
 protein coding gene Chr4:115599879-115602976 (-)
C3H/HeJ MGP_C3HHeJ_G0028368
 protein coding gene Chr4:119044372-119047469 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029095
 protein coding gene Chr4:124162750-124165853 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026379
 protein coding gene Chr4:108975027-108978114 (-)
CAST/EiJ MGP_CASTEiJ_G0027802
 protein coding gene Chr4:116309476-116312580 (-)
CBA/J MGP_CBAJ_G0028335
 protein coding gene Chr4:127572046-127575143 (-)
DBA/2J MGP_DBA2J_G0028483
 protein coding gene Chr4:115573506-115576609 (-)
FVB/NJ MGP_FVBNJ_G0028451
 protein coding gene Chr4:114089580-114092677 (-)
LP/J MGP_LPJ_G0028585
 protein coding gene Chr4:119778377-119781480 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028478
 protein coding gene Chr4:132457019-132460122 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029132
 protein coding gene Chr4:118631120-118634223 (-)
PWK/PhJ MGP_PWKPhJ_G0027528
 protein coding gene Chr4:112407273-112410376 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027351
 protein coding gene Chr4:114939657-114942761 (-)
WSB/EiJ MGP_WSBEiJ_G0027881
 protein coding gene Chr4:118532002-118535099 (-)



Homology
more
  • Human Ortholog
    TMEM125, transmembrane protein 125
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM125, transmembrane protein 125
  • Links
    NCBI Gene ID: 128218
    neXtProt AC: NX_Q96AQ2
    UniProt: Q96AQ2

  • Chr Location
    1p34.2; chr1:43269983-43274002 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    2
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Tmem125
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    9 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    709
  • Tissues
    2
  • cDNA Data
    17
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000050854 Ensembl Gene Model | MGI Sequence Detail 3104 C57BL/6J ±  kb
transcript ENSMUST00000060214 Ensembl | MGI Sequence Detail 1864 Not Applicable  
polypeptide ENSMUSP00000063157 Ensembl | MGI Sequence Detail 216 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140533
References
more
  • Summaries
    All 38
    Developmental Gene Expression 3
    Gene Ontology 1
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:190524 Shalom-Barak T, et al., Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory