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Agbl3 Gene Detail
Summary
  • Symbol
    Agbl3
  • Name
    ATP/GTP binding protein-like 3
  • Synonyms
    2900053G10Rik, 4930431N21Rik, 6530406M24Rik, Ccp3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923473
    NCBI Gene: 76223
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:34757367-34836394 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 15.13 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    1688 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923473
 protein coding gene Chr6:34755249-34837874 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030562
 protein coding gene Chr6:32883770-32965561 (+)
A/J MGP_AJ_G0030535
 protein coding gene Chr6:31472979-31551175 (+)
AKR/J MGP_AKRJ_G0030462
 protein coding gene Chr6:32543206-32623575 (+)
BALB/cJ MGP_BALBcJ_G0030545
 protein coding gene Chr6:31653201-31731551 (+)
C3H/HeJ MGP_C3HHeJ_G0030258
 protein coding gene Chr6:32491863-32572470 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030999
 protein coding gene Chr6:33704807-33786709 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028211
 protein coding gene Chr6:29563451-29643923 (+)
CAST/EiJ MGP_CASTEiJ_G0029660
 protein coding gene Chr6:32316897-32398855 (+)
CBA/J MGP_CBAJ_G0030236
 protein coding gene Chr6:35000934-35092333 (+)
DBA/2J MGP_DBA2J_G0030380
 protein coding gene Chr6:31350347-31429683 (+)
FVB/NJ MGP_FVBNJ_G0030334
 protein coding gene Chr6:31143386-31221764 (+)
LP/J MGP_LPJ_G0030467
 protein coding gene Chr6:32996733-33080697 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030370
 protein coding gene Chr6:37328466-37420294 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031029
 protein coding gene Chr6:32412157-32498194 (+)
PWK/PhJ MGP_PWKPhJ_G0029374
 protein coding gene Chr6:30964102-31047729 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029210
 protein coding gene Chr6:32083537-32180020 (+)
WSB/EiJ MGP_WSBEiJ_G0029736
 protein coding gene Chr6:32342276-32428144 (+)



Homology
more
  • Human Ortholog
    AGBL3, AGBL carboxypeptidase 3
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AGBL3, AGBL carboxypeptidase 3
  • Synonyms
    CCP3
  • Links
    NCBI Gene ID: 340351
    neXtProt AC: NX_Q8NEM8
    UniProt: Q8NEM8

  • Chr Location
    7q33; chr7:134986508-135147963 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    1 phenotype from multigenic genotypes
    4 phenotype references
Homozygous mice for a targeted allele are viable and fertile. Mice homozygous for a knock-out allele exhibit normal response to herpes simplex virus (HSV) and vaccinia virus (VACV) infection.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    13
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    14
  • cDNA Data
    22
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038836 Ensembl Gene Model | MGI Sequence Detail 79028 C57BL/6J ±  kb
transcript ENSMUST00000115016 Ensembl | MGI Sequence Detail 3734 Not Applicable  
polypeptide ENSMUSP00000110668 Ensembl | MGI Sequence Detail 1006 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 24
    cDNA 22
    Primer pair 2

    Microarray probesets 7
Other
Accession IDs
less
MGI:1920224, MGI:1921873
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:343289 Ho KH, et al., Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory