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Rab1b Gene Detail
Summary
  • Symbol
    Rab1b
  • Name
    RAB1B, member RAS oncogene family
  • Synonyms
    1110011F09Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923558
    NCBI Gene: 76308
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:5149235-5157024 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 19, 4.25 cM, cytoband A
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    176 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923558
 protein coding gene Chr19:5149233-5157100 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024693
 protein coding gene Chr19:2026248-2034037 (-)
A/J MGP_AJ_G0024659
 protein coding gene Chr19:1926660-1934450 (-)
AKR/J MGP_AKRJ_G0024632
 protein coding gene Chr19:1974321-1982111 (-)
BALB/cJ MGP_BALBcJ_G0024659
 protein coding gene Chr19:1920129-1927919 (-)
C3H/HeJ MGP_C3HHeJ_G0024427
 protein coding gene Chr19:1976791-1984581 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025106
 protein coding gene Chr19:2083469-2091258 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022536
 protein coding gene Chr19:1854624-1862489 (-)
CAST/EiJ MGP_CASTEiJ_G0023899
 protein coding gene Chr19:2002732-2010523 (-)
CBA/J MGP_CBAJ_G0024398
 protein coding gene Chr19:2166485-2174274 (-)
DBA/2J MGP_DBA2J_G0024526
 protein coding gene Chr19:1909285-1917074 (-)
FVB/NJ MGP_FVBNJ_G0024493
 protein coding gene Chr19:1910499-1918285 (-)
LP/J MGP_LPJ_G0024612
 protein coding gene Chr19:2022614-2030403 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024523
 protein coding gene Chr19:2047855-2055645 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025154
 protein coding gene Chr19:1976527-1984316 (-)
PWK/PhJ MGP_PWKPhJ_G0023645
 protein coding gene Chr19:1946672-1954435 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023450
 protein coding gene Chr19:1965515-1973327 (-)
WSB/EiJ MGP_WSBEiJ_G0023961
 protein coding gene Chr19:1984295-1992208 (-)



Homology
more
  • Human Ortholog
    RAB1B, RAB1B, member RAS oncogene family
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB1B, RAB1B, member RAS oncogene family
  • Links
    NCBI Gene ID: 81876
    neXtProt AC: NX_Q9H0U4
    UniProt: Q9H0U4

  • Chr Location
    11q13.2; chr11:66268590-66277492 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    9 phenotype references
Mice homozygous for a gene trap insertion do not exhibit a detectable mutant phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    22
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    185
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 76308 NCBI Gene Model | MGI Sequence Detail 7790 C57BL/6J ±  kb
transcript NM_029576 RefSeq | MGI Sequence Detail 1835 C57BL/6  
polypeptide Q9D1G1 UniProt | EBI | MGI Sequence Detail 201 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 185
    cDNA 185

    Microarray probesets 2
References
more
  • Summaries
    All 38
    Developmental Gene Expression 1
    Gene Ontology 9
    Phenotypes 9
  • Earliest
    J:28191 Antony C, et al., Developmental regulation of membrane traffic organization during synaptogenesis in mouse diaphragm muscle. J Cell Biol. 1995 Aug;130(4):959-68
  • Latest
    J:316180 Maruyama T, et al., Rap1b Is an Effector of Axin2 Regulating Crosstalk of Signaling Pathways During Skeletal Development. J Bone Miner Res. 2017 Sep;32(9):1816-1828
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory