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Commd9 Gene Detail
Summary
  • Symbol
    Commd9
  • Name
    COMM domain containing 9
  • Synonyms
    1810029F08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923751
    NCBI Gene: 76501
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:101716607-101731984 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 54.07 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    593 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923751
 protein coding gene Chr2:101716592-101731991 (+)
129S1/SvImJ MGP_129S1SvImJ_G0026193
 protein coding gene Chr2:103767192-103784032 (+)
A/J MGP_AJ_G0026154
 protein coding gene Chr2:99493622-99509165 (+)
AKR/J MGP_AKRJ_G0026135
 protein coding gene Chr2:102203210-102218624 (+)
BALB/cJ MGP_BALBcJ_G0026163
 protein coding gene Chr2:99791856-99807271 (+)
C3H/HeJ MGP_C3HHeJ_G0025914
 protein coding gene Chr2:102571852-102587267 (+)
C57BL/6NJ MGP_C57BL6NJ_G0026614
 protein coding gene Chr2:107281416-107296815 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024005
 protein coding gene Chr2:95198476-95213734 (+)
CAST/EiJ MGP_CASTEiJ_G0025379
 protein coding gene Chr2:102985044-103001873 (+)
CBA/J MGP_CBAJ_G0025892
 protein coding gene Chr2:110979544-110994974 (+)
DBA/2J MGP_DBA2J_G0026028
 protein coding gene Chr2:99077915-99093338 (+)
FVB/NJ MGP_FVBNJ_G0025991
 protein coding gene Chr2:98073552-98089105 (+)
LP/J MGP_LPJ_G0026132
 protein coding gene Chr2:103936848-103952253 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026017
 protein coding gene Chr2:114966674-114982133 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0026668
 protein coding gene Chr2:102413829-102429231 (+)
PWK/PhJ MGP_PWKPhJ_G0025114
 protein coding gene Chr2:98552118-98567490 (+)
SPRET/EiJ MGP_SPRETEiJ_G0024915
 protein coding gene Chr2:101625585-101641618 (+)
WSB/EiJ MGP_WSBEiJ_G0025446
 protein coding gene Chr2:103114653-103130961 (+)



Homology
more
  • Human Ortholog
    COMMD9, COMM domain containing 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    COMMD9, COMM domain containing 9
  • Synonyms
    C11orf55, HSPC166, LINC00610
  • Links
    NCBI Gene ID: 29099
    neXtProt AC: NX_Q9P000
    UniProt: Q9P000

  • Chr Location
    11p13; chr11:36269284-36289449 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    28 phenotypes from 3 alleles in 4 genetic backgrounds
    2 images
    20 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit embryonic lethality, neural tube edema, and cardiovascular abnormalities including hemorrhages, heart hypoplasia, focal myocardial wall necrosis and narrowing of the dorsal aortas, and alterations in cranial blood vessels.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    12
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    853
  • Tissues
    50
  • cDNA Data
    66
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 76501 NCBI Gene Model | MGI Sequence Detail 15378 C57BL/6J ±  kb
    transcript NM_029635 RefSeq | MGI Sequence Detail 1175 C57BL/6  
    polypeptide Q8K2Q0 UniProt | EBI | MGI Sequence Detail 198 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 66
      cDNA 66

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2138764
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 4
      Gene Ontology 4
      Phenotypes 20
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory