Wdr26 MGI Mouse Gene Detail - MGI:1923825

Symbol

Wdr26
Name

WD repeat domain 26
Synonyms

1600024A01Rik, Gid7

Feature Type

protein coding gene
IDs

MGI:1923825
NCBI Gene: 226757
Alliance

gene page
Transcription Start Sites

7 TSS

Sequence Map

Chr1:181000793-181039566 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 84.53 cM
Mapping Data

2 experiments

SNPs within 2kb

739 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1923825	protein coding gene	Chr1:181000791-181046211 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0016884	protein coding gene	Chr1:187673404-187713881 (-)
A/J	MGP_AJ_G0016863	protein coding gene	Chr1:180082816-180122848 (-)
AKR/J	MGP_AKRJ_G0016829	protein coding gene	Chr1:185419527-185462730 (-)
BALB/cJ	MGP_BALBcJ_G0016821	protein coding gene	Chr1:180711819-180749567 (-)
C3H/HeJ	MGP_C3HHeJ_G0016646	protein coding gene	Chr1:186206836-186254930 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0017284	protein coding gene	Chr1:193765039-193803522 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0014991	protein coding gene	Chr1:171058646-171096024 (-)
CAST/EiJ	MGP_CASTEiJ_G0016227	protein coding gene	Chr1:185550899-185594287 (-)
CBA/J	MGP_CBAJ_G0016620	protein coding gene	Chr1:200913247-200965827 (-)
DBA/2J	MGP_DBA2J_G0016726	protein coding gene	Chr1:178902254-178941542 (-)
FVB/NJ	MGP_FVBNJ_G0016722	protein coding gene	Chr1:177005519-177042976 (-)
LP/J	MGP_LPJ_G0016800	protein coding gene	Chr1:188922121-188966776 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0016753	protein coding gene	Chr1:208062247-208108936 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0017321	protein coding gene	Chr1:185208308-185249309 (-)
PWK/PhJ	MGP_PWKPhJ_G0016015	protein coding gene	Chr1:178024276-178066014 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0015791	protein coding gene	Chr1:184181332-184219652 (-)
WSB/EiJ	MGP_WSBEiJ_G0016290	protein coding gene	Chr1:185413617-185457082 (-)

Human Ortholog

WDR26, WD repeat domain 26

Vertebrate Orthologs

4

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

WDR26, WD repeat domain 26
Synonyms

CDW2, GID7, MIP2, SKDEAS
Links

HGNC:21208

NCBI Gene ID: 80232

neXtProt AC: NX_Q9H7D7

UniProt: Q9H7D7
Chr Location

1q42.11-q42.12; chr1:224385146-224437033 (-) GRCh38

MGI Vertebrate Homology

Wdr26 stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: WDR26
Gene Tree

Wdr26

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Phenotype Summary

11 phenotype references

All Mutations and Alleles

16
Chemically induced (other)

2
Endonuclease-mediated

4
Gene trapped

7
Targeted

3
Genomic Mutations

2 involving Wdr26
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

44 strains or lines available

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All GO Annotations

10
GO References

3

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

22

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase wdr26

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All Sequences

113
RefSeq

29
UniProt

7
CCDS

CCDS15583.2

Ensembl

ENSMUSG00000038733 (Evidence)
NCBI Gene

226757

			Length	Strain/Species	Flank
genomic	ENSMUSG00000038733	Ensembl Gene Model \| MGI Sequence Detail	38774	C57BL/6J	± kb
transcript	ENSMUST00000237749	Ensembl \| MGI Sequence Detail	7068	Not Applicable
polypeptide	ENSMUSP00000158345	Ensembl \| MGI Sequence Detail	729	Not Applicable

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UniProt

7 Sequences
Protein Ontology

PR:000017390 WD repeat-containing protein 26

(term hierarchy)
InterPro Domains

IPR006595 CTLH, C-terminal LisH motif

IPR020472 G-protein beta WD-40 repeat

IPR006594 LIS1 homology motif

IPR001680 WD40 repeat

IPR036322 WD40-repeat-containing domain superfamily

IPR015943 WD40/YVTN repeat-like-containing domain superfamily

IPR051350 WD repeat-containing signal transduction regulator
GlyGen

Q8C6G8 2 sites, 1 O-linked glycan (2 sites)

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All nucleic 22

cDNA 22

Microarray probesets 13

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MGI:2138242, MGI:2138502, MGI:2138666, MGI:3034821

Summaries

All 39

Gene Ontology 3

Phenotypes 11
Earliest

J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
Latest

J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;

TSS for Wdr26:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr15579	Chr1:181039916-181039940 (-)	-362 bp
Tssr15578	Chr1:181039572-181039577 (-)	-9 bp
Tssr15577	Chr1:181039536-181039565 (-)	15 bp
Tssr15576	Chr1:181039509-181039533 (-)	45 bp
Tssr15575	Chr1:181039281-181039361 (-)	245 bp
Tssr15574	Chr1:181038737-181038761 (-)	817 bp
Tssr15573	Chr1:181002120-181002131 (-)	37,440 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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