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Cpb1 Gene Detail
Summary
  • Symbol
    Cpb1
  • Name
    carboxypeptidase B1
  • Synonyms
    0910001A18Rik, 1810063F02Rik, 2210008M23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1923953
    NCBI Gene: 76703
  • Alliance
    gene page
  • Transcription Start Sites
    33 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:20302428-20329897 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 3, 6.29 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    969 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1923953
 protein coding gene Chr3:20302428-20339681 (-)
129S1/SvImJ MGP_129S1SvImJ_G0027102
 protein coding gene Chr3:17485342-17513970 (-)
A/J MGP_AJ_G0027062
 protein coding gene Chr3:17384508-17410828 (-)
AKR/J MGP_AKRJ_G0027031
 protein coding gene Chr3:17583743-17610025 (-)
BALB/cJ MGP_BALBcJ_G0027074
 protein coding gene Chr3:17129947-17156325 (-)
C3H/HeJ MGP_C3HHeJ_G0026815
 protein coding gene Chr3:17588329-17615281 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027519
 protein coding gene Chr3:18578474-18605964 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024881
 protein coding gene Chr3:15429893-15459234 (-)
CAST/EiJ MGP_CASTEiJ_G0026270
 protein coding gene Chr3:17475880-17506163 (-)
CBA/J MGP_CBAJ_G0026793
 protein coding gene Chr3:18995036-19028676 (-)
DBA/2J MGP_DBA2J_G0026927
 protein coding gene Chr3:16994496-17021281 (-)
FVB/NJ MGP_FVBNJ_G0026895
 protein coding gene Chr3:16651631-16680089 (-)
LP/J MGP_LPJ_G0027039
 protein coding gene Chr3:18118004-18144540 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026916
 protein coding gene Chr3:21041945-21074290 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027579
 protein coding gene Chr3:17346120-17384402 (-)
PWK/PhJ MGP_PWKPhJ_G0026003
 protein coding gene Chr3:16716106-16718413 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025811
 protein coding gene Chr3:17103473-17166304 (-)
WSB/EiJ MGP_WSBEiJ_G0026343
 protein coding gene Chr3:17350491-17380415 (-)



Homology
more
  • Human Ortholog
    CPB1, carboxypeptidase B1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CPB1, carboxypeptidase B1
  • Synonyms
    CPB, PASP, PCPB
  • Links
    NCBI Gene ID: 1360
    neXtProt AC: NX_P15086
    UniProt: P15086

  • Chr Location
    3q24; chr3:148791102-148860187 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    811
  • Tissues
    104
  • cDNA Data
    106
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000011463 Ensembl Gene Model | MGI Sequence Detail 27470 C57BL/6J ±  kb
    transcript ENSMUST00000011607 Ensembl | MGI Sequence Detail 2718 Not Applicable  
    polypeptide ENSMUSP00000011607 Ensembl | MGI Sequence Detail 415 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • EC
      3.4.17.2
    • InterPro Domains
      IPR003146 Carboxypeptidase, activation peptide
      IPR034253 Carboxypeptidase B, carboxypeptidase domain
      IPR036990 Metallocarboxypeptidase-like, propeptide
      IPR000834 Peptidase M14, carboxypeptidase A
    Molecular
    Reagents
    less
    • All nucleic 108
      cDNA 106
      Primer pair 2

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:1915669, MGI:1917103, MGI:2139745
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 4
      Diseases 1
      Gene Ontology 3
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory