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Mospd2 Gene Detail
Summary
  • Symbol
    Mospd2
  • Name
    motile sperm domain containing 2
  • Synonyms
    2410013I23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924013
    NCBI Gene: 76763
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:163719165-163763371 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome X, 76.75 cM, cytoband F5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    945 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924013
protein coding gene ChrX:163719165-163763501 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036259
protein coding gene ChrX:163053124-163097192 (-)
A/J MGP_AJ_G0036229
protein coding gene ChrX:162187994-162232968 (-)
AKR/J MGP_AKRJ_G0036157
protein coding gene ChrX:167422095-167469530 (-)
BALB/cJ MGP_BALBcJ_G0036222
protein coding gene ChrX:160198049-160241535 (-)
C3H/HeJ MGP_C3HHeJ_G0035929
protein coding gene ChrX:163371953-163420832 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036745
protein coding gene ChrX:167819436-167865393 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033565
protein coding gene ChrX:153209753-153251886 (-)
CAST/EiJ MGP_CASTEiJ_G0035217
protein coding gene ChrX:142321131-142369737 (-)
CBA/J MGP_CBAJ_G0035903
protein coding gene ChrX:172705029-172755513 (-)
DBA/2J MGP_DBA2J_G0036069
protein coding gene ChrX:161063515-161109910 (-)
FVB/NJ MGP_FVBNJ_G0036001
protein coding gene ChrX:160199436-160243932 (-)
LP/J MGP_LPJ_G0036154
protein coding gene ChrX:164174062-164217262 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0036033
protein coding gene ChrX:181391401-181436020 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036784
protein coding gene ChrX:162534370-162579283 (-)
PWK/PhJ MGP_PWKPhJ_G0034915
protein coding gene ChrX:139110725-139154372 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034736
protein coding gene ChrX:142834202-142881122 (-)
WSB/EiJ MGP_WSBEiJ_G0035352
protein coding gene ChrX:160472918-160518771 (-)



Homology
more
  • Human Ortholog
    MOSPD2, motile sperm domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MOSPD2, motile sperm domain containing 2
  • Links
    NCBI Gene ID: 158747
    neXtProt AC: NX_Q8NHP6
    UniProt: Q8NHP6

  • Chr Location
    Xp22.2; chrX:14873421-14922327 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000061778 Ensembl Gene Model | MGI Sequence Detail 44207 C57BL/6J ±  kb
transcript ENSMUST00000004715 Ensembl | MGI Sequence Detail 2015 Not Applicable  
polypeptide ENSMUSP00000004715 Ensembl | MGI Sequence Detail 518 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 9
    cDNA 9

    Microarray probesets 6
References
more
  • Summaries
    All 32
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:301755 Yacov N, et al., MOSPD2 is a therapeutic target for the treatment of CNS inflammation. Clin Exp Immunol. 2020 Aug;201(2):105-120

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory