Eid2b MGI Mouse Gene Detail - MGI:1924095 - EP300 interacting inhibitor of differentiation 2B

Symbol

Eid2b
Name

EP300 interacting inhibitor of differentiation 2B
Synonyms

3010005C08Rik

Feature Type

protein coding gene
IDs

MGI:1924095
NCBI Gene: 434156
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr7:27977164-27978914 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 16.67 cM
Mapping Data

1 experiment

SNPs within 2kb

151 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1924095	protein coding gene	Chr7:27977152-27978916 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0031935	protein coding gene	Chr7:27054055-27056478 (+)
A/J	MGP_AJ_G0031914	protein coding gene	Chr7:26397015-26399438 (+)
AKR/J	MGP_AKRJ_G0031845	protein coding gene	Chr7:27072560-27074983 (+)
BALB/cJ	MGP_BALBcJ_G0031920	protein coding gene	Chr7:26557766-26560189 (+)
C3H/HeJ	MGP_C3HHeJ_G0031642	protein coding gene	Chr7:27449550-27451978 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0032385	protein coding gene	Chr7:27922475-27924898 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0029437	protein coding gene	Chr7:27475030-27476826 (+)
CAST/EiJ	MGP_CASTEiJ_G0030977	protein coding gene	Chr7:20748979-20751404 (+)
CBA/J	MGP_CBAJ_G0031605	protein coding gene	Chr7:29177308-29179736 (+)
DBA/2J	MGP_DBA2J_G0031758	protein coding gene	Chr7:26162286-26164709 (+)
FVB/NJ	MGP_FVBNJ_G0031715	protein coding gene	Chr7:26231532-26233955 (+)
LP/J	MGP_LPJ_G0031839	protein coding gene	Chr7:27379604-27382027 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0031750	protein coding gene	Chr7:28682786-28685209 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0032415	protein coding gene	Chr7:26557867-26560290 (+)
PWK/PhJ	MGP_PWKPhJ_G0030700	protein coding gene	Chr7:21162664-21165059 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0030535	protein coding gene	Chr7:17563601-17566013 (+)
WSB/EiJ	MGP_WSBEiJ_G0031084	protein coding gene	Chr7:26883069-26885492 (+)

Human Ortholog

EID2B, EP300 interacting inhibitor of differentiation 2B

Vertebrate Orthologs

1

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

EID2B, EP300 interacting inhibitor of differentiation 2B
Synonyms

EID-2B, EID-3
Links

HGNC:26796

NCBI Gene ID: 126272

neXtProt AC: NX_Q96D98

UniProt: Q96D98
Chr Location

19q13.2; chr19:39530987-39532852 (-) GRCh38

MGI Vertebrate Homology

Eid2b stringent orthology
1 human;1 mouse
HCOP

vertebrate homology predictions: EID2B
Gene Tree

Eid2b

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Phenotype Summary

8 phenotypes from 1 allele in 1 genetic background
3 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

1
Endonuclease-mediated

1
Find Mice (IMSR)

6 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

7
GO References

2

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

12

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

26
RefSeq

2
UniProt

1
CCDS

CCDS52161.1

Ensembl

ENSMUSG00000070705 (Evidence)
NCBI Gene

434156

			Length	Strain/Species	Flank
genomic	ENSMUSG00000070705	Ensembl Gene Model \| MGI Sequence Detail	1751	C57BL/6J	± kb
transcript	ENSMUST00000094651	Ensembl \| MGI Sequence Detail	1751	Not Applicable
polypeptide	ENSMUSP00000092235	Ensembl \| MGI Sequence Detail	151	Not Applicable

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UniProt

1 Sequence
InterPro Domains

IPR033258 EP300-interacting inhibitor of differentiation

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All nucleic 13

cDNA 13

Microarray probesets 1

Summaries

All 18

Gene Ontology 2

Phenotypes 3
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Eid2b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr65456	Chr7:27977142-27977195 (+)	5 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/05/2024 MGI 6.24