About   Help   FAQ
Fam81a Gene Detail
Summary
  • Symbol
    Fam81a
  • Name
    family with sequence similarity 81, member A
  • Synonyms
    6430514L14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924136
    NCBI Gene: 76886
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:69996586-70049840 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 39.27 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1493 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924136
 protein coding gene Chr9:69995793-70049842 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034997
 protein coding gene Chr9:70129792-70187702 (-)
A/J MGP_AJ_G0034978
 protein coding gene Chr9:67708680-67761931 (-)
AKR/J MGP_AKRJ_G0034907
 protein coding gene Chr9:69311701-69365858 (-)
BALB/cJ MGP_BALBcJ_G0034970
 protein coding gene Chr9:67430883-67487315 (-)
C3H/HeJ MGP_C3HHeJ_G0034679
 protein coding gene Chr9:69819313-69876589 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035489
 protein coding gene Chr9:72003254-72061485 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032400
 protein coding gene Chr9:67264215-67317692 (-)
CAST/EiJ MGP_CASTEiJ_G0034001
 protein coding gene Chr9:70090623-70151433 (-)
CBA/J MGP_CBAJ_G0034652
 protein coding gene Chr9:74512834-74572566 (-)
DBA/2J MGP_DBA2J_G0034811
 protein coding gene Chr9:67453128-67506963 (-)
FVB/NJ MGP_FVBNJ_G0034753
 protein coding gene Chr9:66772974-66828509 (-)
LP/J MGP_LPJ_G0034892
 protein coding gene Chr9:70372924-70429064 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034794
 protein coding gene Chr9:75600399-75668971 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035511
 protein coding gene Chr9:69456445-69511842 (-)
PWK/PhJ MGP_PWKPhJ_G0033705
 protein coding gene Chr9:67685579-67744050 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033538
 protein coding gene Chr9:69762209-69817151 (-)
WSB/EiJ MGP_WSBEiJ_G0034113
 protein coding gene Chr9:69348330-69406185 (-)



Homology
more
  • Human Ortholog
    FAM81A, family with sequence similarity 81 member A
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM81A, family with sequence similarity 81 member A
  • Links
    NCBI Gene ID: 145773
    neXtProt AC: NX_Q8TBF8
    UniProt: Q8TBF8

  • Chr Location
    15q22.2; chr15:59372693-59523555 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    818
  • Tissues
    14
  • cDNA Data
    9
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 76886 NCBI Gene Model | MGI Sequence Detail 53255 C57BL/6J ±  kb
    transcript NM_001433746 RefSeq | MGI Sequence Detail 3636 C57BL/6  
    polypeptide Q3UXZ6 UniProt | EBI | MGI Sequence Detail 364 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 4
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 2
      Gene Ontology 3
      Phenotypes 12
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:349402 Kaizuka T, et al., FAM81A is a postsynaptic protein that regulates the condensation of postsynaptic proteins via liquid-liquid phase separation. PLoS Biol. 2024 Mar;22(3):e3002006
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory