Vxn MGI Mouse Gene Detail - MGI:1924232

Symbol

Vxn
Name

vexin
Synonyms

3110035E14Rik, R75066

Feature Type

protein coding gene
IDs

MGI:1924232
NCBI Gene: 76982
Alliance

gene page
Transcription Start Sites

7 TSS

Sequence Map

Chr1:9671492-9697367 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 2.08 cM
Mapping Data

2 experiments

SNPs within 2kb

897 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1924232	protein coding gene	Chr1:9671424-9697368 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0015825	protein coding gene	Chr1:6831830-6862798 (+)
A/J	MGP_AJ_G0015807	protein coding gene	Chr1:6906796-6933525 (+)
AKR/J	MGP_AKRJ_G0015766	protein coding gene	Chr1:6791744-6817231 (+)
BALB/cJ	MGP_BALBcJ_G0015763	protein coding gene	Chr1:6648152-6674102 (+)
C3H/HeJ	MGP_C3HHeJ_G0015597	protein coding gene	Chr1:6714436-6740015 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0016217	protein coding gene	Chr1:7169045-7197693 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0013938	protein coding gene	Chr1:5760694-5787922 (+)
CAST/EiJ	MGP_CASTEiJ_G0015177	protein coding gene	Chr1:6890739-6920177 (+)
CBA/J	MGP_CBAJ_G0015570	protein coding gene	Chr1:7326415-7351987 (+)
DBA/2J	MGP_DBA2J_G0015669	protein coding gene	Chr1:6536424-6563069 (+)
FVB/NJ	MGP_FVBNJ_G0015674	protein coding gene	Chr1:6449938-6477864 (+)
LP/J	MGP_LPJ_G0015741	protein coding gene	Chr1:7056297-7085090 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0015693	protein coding gene	Chr1:7967245-7995707 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0016263	protein coding gene	Chr1:6691360-6720271 (+)
PWK/PhJ	MGP_PWKPhJ_G0014961	protein coding gene	Chr1:6390572-6417934 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0014741	protein coding gene	Chr1:6862209-6887784 (+)
WSB/EiJ	MGP_WSBEiJ_G0015241	protein coding gene	Chr1:6717618-6746178 (+)

Human Ortholog

VXN, vexin

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

VXN, vexin
Synonyms

C8orf46
Links

HGNC:28498

NCBI Gene ID: 254778

neXtProt AC: NX_Q8TAG6

UniProt: Q8TAG6
Chr Location

8q13.1; chr8:66492326-66518524 (+) GRCh38

MGI Vertebrate Homology

Vxn stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: VXN
Gene Tree

Vxn

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Phenotype Summary

6 phenotype references

All Mutations and Alleles

2
Targeted

2
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

17 strains or lines available

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All GO Annotations

5
GO References

2

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

708
Tissues

2
cDNA Data

17
Literature Summary

2

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase vxn

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All Sequences

34
RefSeq

2
UniProt

1
CCDS

CCDS14813.1

Ensembl

ENSMUSG00000067879 (Evidence)
NCBI Gene

76982

			Length	Strain/Species	Flank
genomic	76982	NCBI Gene Model \| MGI Sequence Detail	25876	C57BL/6J	± kb
transcript	NM_178399	RefSeq \| MGI Sequence Detail	3187	C57BL/6
polypeptide	Q8BG31	UniProt \| EBI \| MGI Sequence Detail	207	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000059970 vexin

(term hierarchy)
InterPro Domains

IPR040470 Vexin

IPR027900 Vexin domain

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All nucleic 17

cDNA 17

Microarray probesets 3

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MGI:2138225, MGI:2138522, MGI:2138731, MGI:6156313

Summaries

All 32

Developmental Gene Expression 2

Gene Ontology 2

Phenotypes 6
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Vxn:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr5900	Chr1:9671360-9671369 (+)	-127 bp
Tssr5901	Chr1:9671388-9671481 (+)	-57 bp
Tssr5902	Chr1:9671488-9671535 (+)	20 bp
Tssr5903	Chr1:9671536-9671550 (+)	51 bp
Tssr5904	Chr1:9671561-9671573 (+)	75 bp
Tssr5905	Chr1:9671681-9671712 (+)	205 bp
Tssr5906	Chr1:9671716-9671729 (+)	231 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24