Gpbp1l1 MGI Mouse Gene Detail - MGI:1924360 - GC-rich promoter binding protein 1-like 1

Symbol

Gpbp1l1
Name

GC-rich promoter binding protein 1-like 1
Synonyms

5330440M15Rik, MGC:8183

Feature Type

protein coding gene
IDs

MGI:1924360
NCBI Gene: 77110
Alliance

gene page
Transcription Start Sites

10 TSS

Sequence Map

Chr4:116414855-116451079 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 4, 53.22 cM, cytoband C7
Mapping Data

2 experiments

SNPs within 2kb

841 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1924360	protein coding gene	Chr4:116414357-116451099 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0028627	protein coding gene	Chr4:117456345-117497821 (+)
A/J	MGP_AJ_G0028588	protein coding gene	Chr4:112955770-112992679 (+)
AKR/J	MGP_AKRJ_G0028538	protein coding gene	Chr4:115384815-115434066 (+)
BALB/cJ	MGP_BALBcJ_G0028609	protein coding gene	Chr4:113580189-113617995 (+)
C3H/HeJ	MGP_C3HHeJ_G0028323	protein coding gene	Chr4:116956163-117004039 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0029050	protein coding gene	Chr4:122001086-122041143 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0026334	protein coding gene	Chr4:106994683-107029027 (+)
CAST/EiJ	MGP_CASTEiJ_G0027757	protein coding gene	Chr4:114186303-114229203 (+)
CBA/J	MGP_CBAJ_G0028290	protein coding gene	Chr4:125305875-125349213 (+)
DBA/2J	MGP_DBA2J_G0028438	protein coding gene	Chr4:113587389-113622214 (+)
FVB/NJ	MGP_FVBNJ_G0028406	protein coding gene	Chr4:112088190-112124444 (+)
LP/J	MGP_LPJ_G0028540	protein coding gene	Chr4:117664392-117703919 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0028433	protein coding gene	Chr4:130294251-130340542 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0029087	protein coding gene	Chr4:116544889-116581017 (+)
PWK/PhJ	MGP_PWKPhJ_G0027483	protein coding gene	Chr4:110363889-110400452 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0027306	protein coding gene	Chr4:112815482-112856149 (+)
WSB/EiJ	MGP_WSBEiJ_G0027836	protein coding gene	Chr4:116420225-116459596 (+)

Human Ortholog

GPBP1L1, GC-rich promoter binding protein 1 like 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

GPBP1L1, GC-rich promoter binding protein 1 like 1
Synonyms

SP192
Links

HGNC:28843

NCBI Gene ID: 60313

neXtProt AC: NX_Q9HC44

UniProt: Q9HC44
Chr Location

1p34.1; chr1:45627304-45688113 (-) GRCh38

MGI Vertebrate Homology

Gpbp1l1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: GPBP1L1
Gene Tree

Gpbp1l1

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Phenotype Summary

16 phenotype references

All Mutations and Alleles

81
Chemically induced (other)

2
Gene trapped

75
Radiation induced

1
Targeted

3
Genomic Mutations

4 involving Gpbp1l1
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

31 strains or lines available

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All GO Annotations

7
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

62

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase gpbp1l1

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All Sequences

49
RefSeq

8
UniProt

2
CCDS

CCDS18511.1

Ensembl

ENSMUSG00000034042 (Evidence)
NCBI Gene

77110

			Length	Strain/Species	Flank
genomic	ENSMUSG00000034042	Ensembl Gene Model \| MGI Sequence Detail	36225	C57BL/6J	± kb
transcript	ENSMUST00000030460	Ensembl \| MGI Sequence Detail	3588	Not Applicable
polypeptide	ENSMUSP00000030460	Ensembl \| MGI Sequence Detail	473	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000008162 vasculin-like protein 1

(term hierarchy)
InterPro Domains

IPR028128 Vasculin family

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All nucleic 62

cDNA 62

Microarray probesets 4

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MGI:1933129

Summaries

All 42

Gene Ontology 4

Phenotypes 16
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Gpbp1l1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr38518	Chr4:116414318-116414338 (+)	-527 bp
Tssr38519	Chr4:116414348-116414361 (+)	-500 bp
Tssr38520	Chr4:116414775-116414784 (+)	-75 bp
Tssr38521	Chr4:116414788-116414814 (+)	-54 bp
Tssr38522	Chr4:116414865-116414921 (+)	38 bp
Tssr38523	Chr4:116414937-116414948 (+)	88 bp
Tssr38524	Chr4:116414977-116414996 (+)	132 bp
Tssr38525	Chr4:116415253-116415287 (+)	415 bp
Tssr38526	Chr4:116417344-116417349 (+)	2,492 bp
Tssr38527	Chr4:116450639-116450687 (+)	35,808 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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