Yif1b MGI Mouse Gene Detail - MGI:1924504 - Yip1 interacting factor homolog B (S. cerevisiae)

Symbol

Yif1b
Name

Yip1 interacting factor homolog B (S. cerevisiae)
Synonyms

9430029K10Rik

Feature Type

protein coding gene
IDs

MGI:1924504
NCBI Gene: 77254
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr7:28937754-28947022 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 7, 16.94 cM, cytoband A3
Mapping Data

2 experiments

SNPs within 2kb

356 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1924504	protein coding gene	Chr7:28937019-28947022 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0031978	protein coding gene	Chr7:28148846-28158106 (+)
A/J	MGP_AJ_G0031956	protein coding gene	Chr7:27408867-27418144 (+)
AKR/J	MGP_AKRJ_G0031889	protein coding gene	Chr7:28131713-28140977 (+)
BALB/cJ	MGP_BALBcJ_G0031963	protein coding gene	Chr7:27608462-27617741 (+)
C3H/HeJ	MGP_C3HHeJ_G0031682	protein coding gene	Chr7:28525763-28535025 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0032428	protein coding gene	Chr7:29047624-29057072 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0029478	protein coding gene	Chr7:28463256-28472620 (+)
CAST/EiJ	MGP_CASTEiJ_G0031016	protein coding gene	Chr7:21786149-21796988 (+)
CBA/J	MGP_CBAJ_G0031648	protein coding gene	Chr7:30410020-30419282 (+)
DBA/2J	MGP_DBA2J_G0031800	protein coding gene	Chr7:27152989-27162253 (+)
FVB/NJ	MGP_FVBNJ_G0031757	protein coding gene	Chr7:27262939-27272214 (+)
LP/J	MGP_LPJ_G0031880	protein coding gene	Chr7:28451729-28460993 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0031792	protein coding gene	Chr7:29793362-29802626 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0032457	protein coding gene	Chr7:27614396-27623660 (+)
PWK/PhJ	MGP_PWKPhJ_G0030742	protein coding gene	Chr7:22207397-22217084 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0030575	protein coding gene	Chr7:18623866-18633226 (+)
WSB/EiJ	MGP_WSBEiJ_G0031126	protein coding gene	Chr7:27983412-27992842 (+)

Human Ortholog

YIF1B, Yip1 interacting factor homolog B, membrane trafficking protein

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

YIF1B, Yip1 interacting factor homolog B, membrane trafficking protein
Synonyms

FinGER8, KABAMAS
Links

HGNC:30511

NCBI Gene ID: 90522

neXtProt AC: NX_Q5BJH7

UniProt: Q5BJH7
Chr Location

19q13.2; chr19:38303558-38321887 (-) GRCh38

MGI Vertebrate Homology

Yif1b stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: YIF1B
Gene Tree

Yif1b

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Phenotype Summary

3 phenotypes from 1 allele in 1 genetic background
9 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

17
Endonuclease-mediated

1
Gene trapped

11
Targeted

5
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

23 strains or lines available

Mice homozygous for a knock-out allele exhibit alterations in Golgi vesicle transport and Golgi architecture in pyramidal hippocampal neurons.

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All GO Annotations

23
GO References

8

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

711
Tissues

5
cDNA Data

87
Literature Summary

1

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase yif1b

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All Sequences

53
RefSeq

10
UniProt

4
CCDS

CCDS21069.1, CCDS52171.1

Ensembl

ENSMUSG00000030588 (Evidence)
NCBI Gene

77254

			Length	Strain/Species	Flank
genomic	ENSMUSG00000030588	Ensembl Gene Model \| MGI Sequence Detail	9269	C57BL/6J	± kb
transcript	ENSMUST00000142519	Ensembl \| MGI Sequence Detail	1153	Not Applicable
polypeptide	ENSMUSP00000146477	Ensembl \| MGI Sequence Detail	315	Not Applicable

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UniProt

4 Sequences
Protein Ontology

PR:000017530 protein YIF1B

(term hierarchy)
InterPro Domains

IPR005578 Yif1 family
GlyGen

Q9CX30 3 sites, 1 O-linked glycan (3 sites)

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All nucleic 88

cDNA 87

Primer pair 1

Microarray probesets 3

Summaries

All 36

Developmental Gene Expression 1

Gene Ontology 8

Phenotypes 9
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:315744 Lin X, et al., Unconventional secretion of unglycosylated ORF8 is critical for the cytokine storm during SARS-CoV-2 infection. bioRxiv. 2021 Dec;

TSS for Yif1b:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr65612	Chr7:28937729-28937740 (+)	-19 bp
Tssr65613	Chr7:28937748-28937819 (+)	30 bp
Tssr65614	Chr7:28937859-28937881 (+)	116 bp
Tssr65615	Chr7:28937903-28937932 (+)	164 bp
Tssr65616	Chr7:28937935-28937982 (+)	205 bp
Tssr65617	Chr7:28945164-28945175 (+)	7,416 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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