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Stk31 Gene Detail
Summary
  • Symbol
    Stk31
  • Name
    serine threonine kinase 31
  • Synonyms
    C330007K24Rik, TDRD8
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924735
    NCBI Gene: 77485
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:49372538-49446435 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 23.87 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1515 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924735
 protein coding gene Chr6:49372441-49446440 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030725
 protein coding gene Chr6:48414037-48504954 (+)
A/J MGP_AJ_G0030696
 protein coding gene Chr6:46203795-46285029 (+)
AKR/J MGP_AKRJ_G0030621
 protein coding gene Chr6:47834669-47919805 (+)
BALB/cJ MGP_BALBcJ_G0030706
 protein coding gene Chr6:46548350-46625887 (+)
C3H/HeJ MGP_C3HHeJ_G0030419
 protein coding gene Chr6:47843916-47926887 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031161
 protein coding gene Chr6:49553492-49646654 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028368
 protein coding gene Chr6:43802777-43881717 (+)
CAST/EiJ MGP_CASTEiJ_G0029823
 protein coding gene Chr6:47555101-47641053 (+)
CBA/J MGP_CBAJ_G0030394
 protein coding gene Chr6:51618570-51715903 (+)
DBA/2J MGP_DBA2J_G0030543
 protein coding gene Chr6:46112764-46189638 (+)
FVB/NJ MGP_FVBNJ_G0030495
 protein coding gene Chr6:45751000-45828934 (+)
LP/J MGP_LPJ_G0030628
 protein coding gene Chr6:48385512-48478284 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030529
 protein coding gene Chr6:54364308-54468904 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0031190
 protein coding gene Chr6:47716563-47796244 (+)
PWK/PhJ MGP_PWKPhJ_G0029535
 protein coding gene Chr6:45663439-45743515 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029371
 protein coding gene Chr6:47040932-47120230 (+)
WSB/EiJ MGP_WSBEiJ_G0029900
 protein coding gene Chr6:47696613-47777550 (+)



Homology
more
  • Human Ortholog
    STK31, serine/threonine kinase 31
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STK31, serine/threonine kinase 31
  • Synonyms
    SGK396, TDRD8
  • Links
    NCBI Gene ID: 56164
    neXtProt AC: NX_Q9BXU1
    UniProt: Q9BXU1

  • Chr Location
    7p15.3; chr7:23710082-23832513 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 3 alleles in 5 genetic backgrounds
    11 phenotype references
Mice homozygous for a null mutation display normal embryonic development and spermatogenesis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    1
  • cDNA Data
    7
  • Literature Summary
    3
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023403 Ensembl Gene Model | MGI Sequence Detail 73898 C57BL/6J ±  kb
transcript ENSMUST00000024171 Ensembl | MGI Sequence Detail 3237 Not Applicable  
polypeptide ENSMUSP00000024171 Ensembl | MGI Sequence Detail 1018 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 8
    cDNA 7
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory