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Shisa4 Gene Detail
Summary
  • Symbol
    Shisa4
  • Name
    shisa family member 4
  • Synonyms
    9330132O05Rik, Tmem58
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924802
    NCBI Gene: 77552
  • Alliance
    gene page
  • Transcription Start Sites
    17 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:135298795-135302975 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 58.58 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    164 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924802
 protein coding gene Chr1:135298578-135302975 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016523
 protein coding gene Chr1:139136062-139140192 (-)
A/J MGP_AJ_G0016506
 protein coding gene Chr1:133873395-133877532 (-)
AKR/J MGP_AKRJ_G0016471
 protein coding gene Chr1:137852058-137856189 (-)
BALB/cJ MGP_BALBcJ_G0016466
 protein coding gene Chr1:134188149-134192329 (-)
C3H/HeJ MGP_C3HHeJ_G0016292
 protein coding gene Chr1:137950403-137954537 (-)
C57BL/6NJ MGP_C57BL6NJ_G0016927
 protein coding gene Chr1:144161052-144165232 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0014638
 protein coding gene Chr1:126974153-126978250 (-)
CAST/EiJ MGP_CASTEiJ_G0015872
 protein coding gene Chr1:137030070-137034258 (-)
CBA/J MGP_CBAJ_G0016265
 protein coding gene Chr1:149145369-149152973 (-)
DBA/2J MGP_DBA2J_G0016371
 protein coding gene Chr1:132867269-132871404 (-)
FVB/NJ MGP_FVBNJ_G0016370
 protein coding gene Chr1:131506753-131512572 (-)
LP/J MGP_LPJ_G0016442
 protein coding gene Chr1:140368900-140374738 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016395
 protein coding gene Chr1:154823554-154827754 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016963
 protein coding gene Chr1:137610968-137615136 (-)
PWK/PhJ MGP_PWKPhJ_G0015658
 protein coding gene Chr1:131895566-131899831 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015445
 protein coding gene Chr1:136580685-136584814 (-)
WSB/EiJ MGP_WSBEiJ_G0015935
 protein coding gene Chr1:137651078-137657953 (-)



Homology
more
  • Human Ortholog
    SHISA4, shisa family member 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SHISA4, shisa family member 4
  • Synonyms
    C1orf40, TMEM58
  • Links
    NCBI Gene ID: 149345
    neXtProt AC: NX_Q96DD7
    UniProt: Q96DD7

  • Chr Location
    1q32.1; chr1:201888677-201892587 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 2 alleles in 2 genetic backgrounds
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are fertile and phenotypically normal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    762
  • Tissues
    37
  • cDNA Data
    5
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000041889 Ensembl Gene Model | MGI Sequence Detail 4181 C57BL/6J ±  kb
transcript ENSMUST00000041240 Ensembl | MGI Sequence Detail 1763 Not Applicable  
polypeptide ENSMUSP00000046033 Ensembl | MGI Sequence Detail 197 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    Genomic 1
    cDNA 5

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 13
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory