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Odad3 Gene Detail
Summary
  • Symbol
    Odad3
  • Name
    outer dynein arm docking complex subunit 3
  • Synonyms
    b2b1885Clo, C330001K17Rik, Ccdc151
  • Feature Type
    protein coding gene
  • IDs
    MGI:1924859
    NCBI Gene: 77609
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:21901167-21913930 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 8.01 cM, cytoband A4
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    406 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1924859
 protein coding gene Chr9:21901167-21914268 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034472
 protein coding gene Chr9:19265248-19277947 (-)
A/J MGP_AJ_G0034450
 protein coding gene Chr9:18894016-18906724 (-)
AKR/J MGP_AKRJ_G0034376
 protein coding gene Chr9:19260267-19272973 (-)
BALB/cJ MGP_BALBcJ_G0034441
 protein coding gene Chr9:18775865-18788848 (-)
C3H/HeJ MGP_C3HHeJ_G0034153
 protein coding gene Chr9:19560333-19575532 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034962
 protein coding gene Chr9:20020282-20036309 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031892
 protein coding gene Chr9:17994066-18007257 (-)
CAST/EiJ MGP_CASTEiJ_G0033476
 protein coding gene Chr9:19398980-19412934 (-)
CBA/J MGP_CBAJ_G0034126
 protein coding gene Chr9:20810245-20826598 (-)
DBA/2J MGP_DBA2J_G0034284
 protein coding gene Chr9:18857475-18870731 (-)
FVB/NJ MGP_FVBNJ_G0034227
 protein coding gene Chr9:18406763-18420622 (-)
LP/J MGP_LPJ_G0034370
 protein coding gene Chr9:19414387-19431210 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034271
 protein coding gene Chr9:22368439-22385615 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0034982
 protein coding gene Chr9:19220344-19237320 (-)
PWK/PhJ MGP_PWKPhJ_G0033181
 protein coding gene Chr9:18863118-18877265 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033015
 protein coding gene Chr9:19266077-19278830 (-)
WSB/EiJ MGP_WSBEiJ_G0033591
 protein coding gene Chr9:18949054-18975600 (-)



Homology
more
  • Human Ortholog
    ODAD3, outer dynein arm docking complex subunit 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ODAD3, outer dynein arm docking complex subunit 3
  • Synonyms
    CCDC151, CILD30, ODA10
  • Links
    NCBI Gene ID: 115948
    neXtProt AC: NX_A5D8V7
    UniProt: A5D8V7

  • Chr Location
    19p13.2; chr19:11420604-11435782 (-)  GRCh38
Human Diseases
more
  • Diseases
    2 with Odad3 mouse models; 1 with human ODAD3 associations

Human Disease Mouse Models
      
IDs
 View 2 models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    2 with disease annotations
  • References
    2 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotypes from 3 alleles in 4 genetic backgrounds
    6 images
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mico homozygous for an ENU-induced allele exhibit dextrocardia associated with situs inversus totalis and hypoplastic spleen, adrenal anomalies and immotile/dyskinetic tracheal airway cilia. Mice homozygous for a conditional allele activated ubiquitously in adults exhibit reduced sperm number and motility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    41
  • GO References
    9
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    736
  • Tissues
    13
  • cDNA Data
    13
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039632 Ensembl Gene Model | MGI Sequence Detail 12764 C57BL/6J ±  kb
    transcript ENSMUST00000115336 Ensembl | MGI Sequence Detail 2103 Not Applicable  
    polypeptide ENSMUSP00000110993 Ensembl | MGI Sequence Detail 594 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 19
      cDNA 13
      Primer pair 6

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2143105, MGI:5445349, MGI:6459976
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 2
      Diseases 2
      Gene Ontology 9
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:350072 Pasquini M, et al., The Odad3 Gene Is Necessary for Spermatozoa Development and Male Fertility in Mice. Cells. 2024 Jun 18;13(12)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory