Krtap10-4 MGI Mouse Gene Detail - MGI:1925013 - keratin associated protein 10-4

Symbol

Krtap10-4
Name

keratin associated protein 10-4
Synonyms

A030009A09Rik

Feature Type

protein coding gene
IDs

MGI:1925013
NCBI Gene: 100191037
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr10:77662003-77662904 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 10, 39.72 cM
Mapping Data

2 experiments

SNPs within 2kb

168 from dbSNP Build 142
Strain Annotations

15

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1925013	protein coding gene	Chr10:77661949-77662929 (-)
129S1/SvImJ	no annotation
A/J	MGP_AJ_G0017386	protein coding gene	Chr10:75506973-75507953 (-)
AKR/J	MGP_AKRJ_G0017349	protein coding gene	Chr10:77534028-77534933 (-)
BALB/cJ	MGP_BALBcJ_G0017348	protein coding gene	Chr10:75688107-75689690 (-)
C3H/HeJ	MGP_C3HHeJ_G0017172	protein coding gene	Chr10:77656723-77657616 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0017804	protein coding gene	Chr10:80974636-80975616 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0015495	protein coding gene	Chr10:71869883-71870880 (-)
CAST/EiJ	MGP_CASTEiJ_G0016741	protein coding gene	Chr10:77940195-77943003 (-)
CBA/J	MGP_CBAJ_G0017144	protein coding gene	Chr10:84102484-84106267 (+)
DBA/2J	MGP_DBA2J_G0017251	protein coding gene	Chr10:74754850-74755830 (-)
FVB/NJ	MGP_FVBNJ_G0017243	protein coding gene	Chr10:73925925-73927509 (-)
LP/J	no annotation
NOD/ShiLtJ	MGP_NODShiLtJ_G0017270	protein coding gene	Chr10:86075826-86076806 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0017846	protein coding gene	Chr10:77571784-77574098 (-)
PWK/PhJ	MGP_PWKPhJ_G0016524	protein coding gene	Chr10:74679992-74680836 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0016309	protein coding gene	Chr10:76826353-76827405 (+)
WSB/EiJ	no annotation

Human Ortholog

KRTAP10-10, keratin associated protein 10-10

Vertebrate Orthologs

9

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

KRTAP10-10, keratin associated protein 10-10
Synonyms

KAP10.10, KAP18.10, KRTAP18-10, KRTAP18.10
Links

HGNC:22972

NCBI Gene ID: 353333

neXtProt AC: NX_P60014

UniProt: P60014
Chr Location

21q22.3; chr21:44637356-44638455 (+) GRCh38

Human Ortholog

KRTAP10-3, keratin associated protein 10-3
Synonyms

KAP10.3, KAP18-3, KAP18.3, KRTAP10.3, KRTAP18-3, KRTAP18.3
Links

HGNC:22968

NCBI Gene ID: 386682

neXtProt AC: NX_P60369

UniProt: P60369
Chr Location

21q22.3

Human Ortholog

KRTAP10-7, keratin associated protein 10-7
Synonyms

KAP10.7, KAP18.7, KRTAP18-7
Links

HGNC:22970

NCBI Gene ID: 386675

neXtProt AC: NX_P60409

UniProt: P60409
Chr Location

21q22.3; chr21:44600597-44602174 (+) GRCh38

MGI Vertebrate Homology

Krtap10-4 stringent orthology
3 human;1 mouse;6 rat
HCOP

vertebrate homology predictions: KRTAP10-10, KRTAP10-3, KRTAP10-7
Gene Tree

Krtap10-4

less

References

2 with disease annotations

less

Phenotype Summary

28 phenotype references

All Mutations and Alleles

4
Chemically induced (other)

1
Targeted

3
Genomic Mutations

4 involving Krtap10-4
Find Mice (IMSR)

4 strains or lines available

less

All GO Annotations

1
GO References

1

Molecular Function

Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.

Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

5

Tissue x Stage Matrix

Other Mouse Links

GEO

Expression Atlas

less

All Sequences

26
RefSeq

2
UniProt

1
CCDS

CCDS78848.1

Ensembl

ENSMUSG00000069582 (Evidence)
NCBI Gene

100191037

			Length	Strain/Species	Flank
genomic	100191037	NCBI Gene Model \| MGI Sequence Detail	902	C57BL/6J	± kb
transcript	NM_001135991	RefSeq \| MGI Sequence Detail	902	Not Specified
polypeptide	NP_001129463	RefSeq \| MGI Sequence Detail	221	Not Specified

less

UniProt

1 Sequence
InterPro Domains

IPR002494 Keratin-associated protein

less

All nucleic 6

cDNA 5

Primer pair 1

Microarray probesets 2

less

MGI:2143497

Summaries

All 45

Diseases 2

Gene Ontology 1

Phenotypes 28
Earliest

J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
Latest

J:351211 Wu Y, et al., Cathepsin B abundance, activity and microglial localisation in Alzheimer's disease-Down syndrome and early onset Alzheimer's disease; the role of elevated cystatin B. Acta Neuropathol Commun. 2023 Aug 14;11(1):132

TSS for Krtap10-4:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr98250	Chr10:77662926-77662931 (-)	-25 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24