Krtap19-3 Gene Detail

Summary

• Symbol
  Krtap19-3
• Name
  keratin associated protein 19-3
• Synonyms
  A030006N06Rik, Krtap16-5

• Feature Type
  protein coding gene
• IDs
  MGI:1925168
  NCBI Gene: 77918
• Alliance
  gene page
• Transcription Start Sites
  1 TSS

Location &
Maps

• Sequence Map
  Chr16:88674401-88674926 bp, - strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 16, 51.42 cM, cytoband C3.3
• Mapping Data
  4 experiments

Strain
Comparison

• SNPs within 2kb
  131 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1925168	protein coding gene	Chr16:88674401-88674926 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0022999	protein coding gene	Chr16:89698539-89699065 (-)
A/J	MGP_AJ_G0022967	protein coding gene	Chr16:85536714-85537239 (-)
AKR/J	MGP_AKRJ_G0022937	protein coding gene	Chr16:88142977-88143514 (-)
BALB/cJ	MGP_BALBcJ_G0022969	protein coding gene	Chr16:86068616-86069141 (-)
C3H/HeJ	MGP_C3HHeJ_G0022730	protein coding gene	Chr16:88706910-88707435 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0023416	protein coding gene	Chr16:92580212-92580737 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0020919	protein coding gene	Chr16:83352141-83352720 (-)
CAST/EiJ	MGP_CASTEiJ_G0022251	protein coding gene	Chr16:89140399-89140924 (-)
CBA/J	MGP_CBAJ_G0022699	protein coding gene	Chr16:96545677-96546214 (-)
DBA/2J	MGP_DBA2J_G0022833	protein coding gene	Chr16:85464731-85465268 (-)
FVB/NJ	MGP_FVBNJ_G0022808	protein coding gene	Chr16:84566045-84566570 (-)
LP/J	MGP_LPJ_G0022903	protein coding gene	Chr16:89390600-89391126 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0022828	protein coding gene	Chr16:101110180-101110705 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0023434	protein coding gene	Chr16:88637146-88637672 (-)
PWK/PhJ	MGP_PWKPhJ_G0021996	protein coding gene	Chr16:85625271-85625808 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0021826	protein coding gene	Chr16:88197277-88197814 (-)
WSB/EiJ	MGP_WSBEiJ_G0022301	protein coding gene	Chr16:88869447-88869972 (-)

Homology

• Human Ortholog
  KRTAP19-3, keratin associated protein 19-3

• Vertebrate Orthologs
  4

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  KRTAP19-3, keratin associated protein 19-3
  
• Synonyms
  GTRHP, KAP19.3
• Links
  HGNC:18938

  NCBI Gene ID: 337970

  neXtProt AC: NX_Q7Z4W3

  UniProt: Q7Z4W3

  
  
• Chr Location
  21q22.11; chr21:30491462-30492013 (-)  GRCh38

---

• Human Ortholog
  KRTAP19-5, keratin associated protein 19-5
  
• Synonyms
  KAP19.5
• Links
  HGNC:18940

  NCBI Gene ID: 337972

  neXtProt AC: NX_Q3LI72

  UniProt: Q3LI72

  
  
• Chr Location
  21q22.11; chr21:30501657-30502141 (-)  GRCh38

---

• Human Ortholog
  KRTAP19-6, keratin associated protein 19-6
  
• Synonyms
  KAP19.6
• Links
  HGNC:18941

  NCBI Gene ID: 337973

  neXtProt AC: NX_Q3LI70

  UniProt: Q3LI70

  
  
• Chr Location
  21q22.11; chr21:30541535-30541864 (-)  GRCh38

---

• MGI Vertebrate Homology
  Krtap19-3 stringent orthology
  3 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: KRTAP19-3, KRTAP19-5, KRTAP19-6
• Gene Tree
  Krtap19-3
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  3
• Targeted
  2
• Genomic Mutations
  3 involving Krtap19-3
• Find Mice (IMSR)
  4 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  2
• GO References
  2

Expression

• Assay Results
  706
• cDNA Data
  13
• Literature Summary
  1

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  29
• RefSeq
  2
• UniProt
  1
• CCDS
  CCDS49895.1

• Ensembl
  ENSMUSG00000060469 (Evidence)
• NCBI Gene
  77918

Representative Sequences			Length	Strain/Species
genomic	77918	NCBI Gene Model | MGI Sequence Detail	526	C57BL/6J
transcript	NM_130857	RefSeq | MGI Sequence Detail	526	C57BL/6
polypeptide	Q925H6	UniProt | EBI | MGI Sequence Detail	87	Not Applicable

Protein
Information

• UniProt
  1 Sequence
• Protein Ontology
  PR:000009633 keratin-associated protein 16-5
  (term hierarchy)
• InterPro Domains
  IPR051528 Keratin-associated protein type 19
  IPR021743 Keratin-associated protein, type8/19/20/21/22

Molecular
Reagents

• All nucleic 13

  cDNA 13

  
  

  Microarray probesets 2

References

• Summaries
  All 27

  Developmental Gene Expression 1

  Gene Ontology 2

  Phenotypes 6
• Earliest
  J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
• Latest
  J:335294 Redhead Y, et al., Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes. Development. 2023 Apr 15;150(8):dev201077

TSS for Krtap19-3:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr141974	Chr16:88674919-88674928 (-)	2 bp