Sh2d4b MGI Mouse Gene Detail - MGI:1925182

Sequence Map

Chr14:40535746-40615223 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1925182	protein coding gene	Chr14:40533478-40624294 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0021191	protein coding gene	Chr14:34436006-34515991 (-)
A/J	MGP_AJ_G0021139	protein coding gene	Chr14:33103988-33176340 (-)
AKR/J	MGP_AKRJ_G0021116	protein coding gene	Chr14:34457746-34537337 (-)
BALB/cJ	MGP_BALBcJ_G0021143	protein coding gene	Chr14:33323258-33395796 (-)
C3H/HeJ	MGP_C3HHeJ_G0020926	protein coding gene	Chr14:34410893-34491049 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0021575	protein coding gene	Chr14:35824334-35910920 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0019137	protein coding gene	Chr14:32735102-32810775 (-)
CAST/EiJ	MGP_CASTEiJ_G0020451	protein coding gene	Chr14:34184114-34267697 (-)
CBA/J	MGP_CBAJ_G0020892	protein coding gene	Chr14:37043572-37127705 (-)
DBA/2J	MGP_DBA2J_G0021015	protein coding gene	Chr14:33060254-33130756 (-)
FVB/NJ	MGP_FVBNJ_G0020999	protein coding gene	Chr14:32999624-33073426 (-)
LP/J	MGP_LPJ_G0021084	protein coding gene	Chr14:34643455-34731513 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0021025	protein coding gene	Chr14:36688936-36766254 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0021608	protein coding gene	Chr14:34240036-34323636 (-)
PWK/PhJ	MGP_PWKPhJ_G0020199	protein coding gene	Chr14:32535506-32610998 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0020023	protein coding gene	Chr14:33863399-33946232 (-)
WSB/EiJ	MGP_WSBEiJ_G0020506	protein coding gene	Chr14:34343483-34430434 (-)

Vertebrate Orthology Source

Alliance of Genome Resources

MGI Vertebrate Homology

Sh2d4b stringent orthology
1 human;1 mouse;1 rat;2 zebrafish
HCOP

vertebrate homology predictions: SH2D4B
Gene Tree

Sh2d4b

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Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

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			Length	Strain/Species	Flank
genomic	ENSMUSG00000037833	Ensembl Gene Model \| MGI Sequence Detail	79478	C57BL/6J	± kb
transcript	ENSMUST00000096000	Ensembl \| MGI Sequence Detail	1597	Not Applicable
polypeptide	ENSMUSP00000093699	Ensembl \| MGI Sequence Detail	431	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000030958 SH2 domain-containing protein 4B

(term hierarchy)
InterPro Domains

IPR035839 SH2D4B, SH2 domain

IPR000980 SH2 domain

IPR036860 SH2 domain superfamily

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Summaries

All 21

Developmental Gene Expression 2

Gene Ontology 1

Phenotypes 2
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034

TSS for Sh2d4b:

(View these features in JBrowse)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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