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Fam53b Gene Detail
Summary
  • Symbol
    Fam53b
  • Name
    family with sequence similarity 53, member B
  • Synonyms
    A930008G19Rik, MGC:40647, mKIAA0140
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925188
    NCBI Gene: 77938
  • Alliance
    gene page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:132313811-132415615 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 76.31 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    2399 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925188
 protein coding gene Chr7:132313811-132429518 (-)
129S1/SvImJ MGP_129S1SvImJ_G0033115
 protein coding gene Chr7:137416601-137520469 (-)
A/J MGP_AJ_G0033097
 protein coding gene Chr7:133631338-133732215 (-)
AKR/J MGP_AKRJ_G0033029
 protein coding gene Chr7:137199005-137296984 (-)
BALB/cJ MGP_BALBcJ_G0033098
 protein coding gene Chr7:133315528-133416526 (-)
C3H/HeJ MGP_C3HHeJ_G0032812
 protein coding gene Chr7:137031316-137135034 (-)
C57BL/6NJ MGP_C57BL6NJ_G0033609
 protein coding gene Chr7:142649716-142756922 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0030580
 protein coding gene Chr7:134911841-135013511 (-)
CAST/EiJ MGP_CASTEiJ_G0032142
 protein coding gene Chr7:128943398-129047094 (-)
CBA/J MGP_CBAJ_G0032785
 protein coding gene Chr7:147479145-147588720 (-)
DBA/2J MGP_DBA2J_G0032937
 protein coding gene Chr7:131645448-131746774 (-)
FVB/NJ MGP_FVBNJ_G0032890
 protein coding gene Chr7:131486787-131585841 (-)
LP/J MGP_LPJ_G0033031
 protein coding gene Chr7:138934565-139038564 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032922
 protein coding gene Chr7:148407074-148509829 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0033629
 protein coding gene Chr7:136181318-136290085 (-)
PWK/PhJ MGP_PWKPhJ_G0031848
 protein coding gene Chr7:124668147-124769189 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031694
 protein coding gene Chr7:122975828-123075672 (-)
WSB/EiJ MGP_WSBEiJ_G0032253
 protein coding gene Chr7:137089190-137194370 (-)



Homology
more
  • Human Ortholog
    FAM53B, family with sequence similarity 53 member B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FAM53B, family with sequence similarity 53 member B
  • Synonyms
    bA12J10.2, KIAA0140, smp
  • Links
    NCBI Gene ID: 9679
    neXtProt AC: NX_Q14153
    UniProt: Q14153

  • Chr Location
    10q26.13; chr10:124619292-124744378 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    733
  • Tissues
    19
  • cDNA Data
    62
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000030956 Ensembl Gene Model | MGI Sequence Detail 101805 C57BL/6J ±  kb
    transcript ENSMUST00000097999 Ensembl | MGI Sequence Detail 5465 Not Applicable  
    polypeptide ENSMUSP00000095608 Ensembl | MGI Sequence Detail 422 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 63
      cDNA 63

      Microarray probesets 3
    References
    more
    • Summaries
      All 39
      Developmental Gene Expression 5
      Gene Ontology 4
      Phenotypes 8
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:353626 Ohkawara B, et al., Transcriptome profile of subsynaptic myonuclei at the neuromuscular junction in embryogenesis. J Neurochem. 2024 Apr;168(4):342-354
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory