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Dnajc21 Gene Detail
Summary
  • Symbol
    Dnajc21
  • Name
    DnaJ heat shock protein family (Hsp40) member C21
  • Synonyms
    4930461P20Rik, 9930116P15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925371
    NCBI Gene: 78244
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:10446842-10470602 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 5.35 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    812 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925371
 protein coding gene Chr15:10446842-10470685 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021721
 protein coding gene Chr15:7580851-7607041 (-)
A/J MGP_AJ_G0021681
 protein coding gene Chr15:7380140-7403402 (-)
AKR/J MGP_AKRJ_G0021659
 protein coding gene Chr15:7549012-7575803 (-)
BALB/cJ MGP_BALBcJ_G0021688
 protein coding gene Chr15:7296950-7320136 (-)
C3H/HeJ MGP_C3HHeJ_G0021464
 protein coding gene Chr15:7500556-7524985 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022127
 protein coding gene Chr15:7867064-7892356 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019664
 protein coding gene Chr15:6853006-6877512 (-)
CAST/EiJ MGP_CASTEiJ_G0020980
 protein coding gene Chr15:7553794-7580860 (-)
CBA/J MGP_CBAJ_G0021433
 protein coding gene Chr15:8043932-8072452 (-)
DBA/2J MGP_DBA2J_G0021557
 protein coding gene Chr15:7250068-7273684 (-)
FVB/NJ MGP_FVBNJ_G0021535
 protein coding gene Chr15:7110466-7133680 (-)
LP/J MGP_LPJ_G0021625
 protein coding gene Chr15:7481198-7506414 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021560
 protein coding gene Chr15:8334744-8359513 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022150
 protein coding gene Chr15:7514678-7541603 (-)
PWK/PhJ MGP_PWKPhJ_G0020723
 protein coding gene Chr15:7412932-7437849 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020561
 protein coding gene Chr15:7470403-7493728 (-)
WSB/EiJ MGP_WSBEiJ_G0021036
 protein coding gene Chr15:7528976-7552771 (-)



Homology
more
  • Human Ortholog
    DNAJC21, DnaJ heat shock protein family (Hsp40) member C21
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DNAJC21, DnaJ heat shock protein family (Hsp40) member C21
  • Synonyms
    BMFS3, DNAJA5, GS3, JJJ1
  • Links
    NCBI Gene ID: 134218
    neXtProt AC: NX_Q5F1R6
    UniProt: Q5F1R6

  • Chr Location
    5p13.2; chr5:34929559-34958964 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    761
  • Tissues
    34
  • cDNA Data
    50
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000044224 Ensembl Gene Model | MGI Sequence Detail 23761 C57BL/6J ±  kb
    transcript ENSMUST00000136591 Ensembl | MGI Sequence Detail 2060 Not Applicable  
    polypeptide ENSMUSP00000116865 Ensembl | MGI Sequence Detail 531 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 50
      cDNA 50

      Microarray probesets 6
    Other
    Accession IDs
    less
    MGI:1925494
    References
    more
    • Summaries
      All 40
      Developmental Gene Expression 3
      Gene Ontology 5
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory