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Trappc6b Gene Detail
Summary
  • Symbol
    Trappc6b
  • Name
    trafficking protein particle complex 6B
  • Synonyms
    5830498C14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925482
    NCBI Gene: 78232
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:59089878-59108258 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 25.99 cM, cytoband C2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    763 from dbSNP Build 142
  • Strain Annotations
    17
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925482
 protein coding gene Chr12:59089878-59108258 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019767
 protein coding gene Chr12:58234043-58256520 (-)
A/J MGP_AJ_G0019726
 protein coding gene Chr12:56120476-56139472 (-)
AKR/J MGP_AKRJ_G0019701
 protein coding gene Chr12:57904640-57923024 (-)
BALB/cJ MGP_BALBcJ_G0019706
 protein coding gene Chr12:56502680-56520907 (-)
C3H/HeJ MGP_C3HHeJ_G0019511
 protein coding gene Chr12:58002909-58022356 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020158
 protein coding gene Chr12:59943431-59976614 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017778
 protein coding gene Chr12:54495618-54513476 (-)
CAST/EiJ MGP_CASTEiJ_G0019063
 protein coding gene Chr12:52896210-52914330 (-)
CBA/J MGP_CBAJ_G0019480
 protein coding gene Chr12:62155156-62178496 (-)
DBA/2J MGP_DBA2J_G0019596
 protein coding gene Chr12:56035050-56053730 (-)
FVB/NJ MGP_FVBNJ_G0019584
 protein coding gene Chr12:55304616-55322976 (-)
LP/J MGP_LPJ_G0019668
 protein coding gene Chr12:58278895-58299899 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019622
 protein coding gene Chr12:63757038-63776658 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020192
 protein coding gene Chr12:57350034-57370490 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0018623
 protein coding gene Chr12:51747464-51772039 (-)
WSB/EiJ MGP_WSBEiJ_G0019114
 protein coding gene Chr12:57914382-57934510 (-)



Homology
more
  • Human Ortholog
    TRAPPC6B, trafficking protein particle complex subunit 6B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TRAPPC6B, trafficking protein particle complex subunit 6B
  • Synonyms
    NEDMEBA, TPC6
  • Links
    NCBI Gene ID: 122553
    neXtProt AC: NX_Q86SZ2
    UniProt: Q86SZ2

  • Chr Location
    14q21.1; chr14:39147811-39170532 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human TRAPPC6B associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    756
  • Tissues
    10
  • cDNA Data
    11
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 78232 NCBI Gene Model | MGI Sequence Detail 18381 C57BL/6J ±  kb
transcript NM_001306218 RefSeq | MGI Sequence Detail 1539 C57BL/6  
polypeptide Q9D289 UniProt | EBI | MGI Sequence Detail 158 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • Protein Ontology
    PR:000016618 trafficking protein particle complex subunit 6B
    (term hierarchy)
  • InterPro Domains
    IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily
    IPR007194 Transport protein particle (TRAPP) component
    IPR037992 TRAPP complex, Trs33 subunit
  • GlyGen
    Q9D289 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139485
References
more
  • Summaries
    All 36
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:320033 Kim JJ, et al., TRAPP Complexes in Secretion and Autophagy. Front Cell Dev Biol. 2016;4:20
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory