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Iqch Gene Detail
Summary
  • Symbol
    Iqch
  • Name
    IQ motif containing H
  • Synonyms
    4921504K03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925500
    NCBI Gene: 78250
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:63328737-63509775 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 34.08 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3735 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925500
 protein coding gene Chr9:63328522-63509808 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034930
 protein coding gene Chr9:63016445-63214128 (-)
A/J MGP_AJ_G0034910
 protein coding gene Chr9:60927751-61110133 (-)
AKR/J MGP_AKRJ_G0034840
 protein coding gene Chr9:62344084-62529112 (-)
BALB/cJ MGP_BALBcJ_G0034903
 protein coding gene Chr9:60654666-60837457 (-)
C3H/HeJ MGP_C3HHeJ_G0034613
 protein coding gene Chr9:62860196-63050131 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035422
 protein coding gene Chr9:64746388-64933163 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032333
 protein coding gene Chr9:60587806-60771167 (-)
CAST/EiJ MGP_CASTEiJ_G0033934
 protein coding gene Chr9:63008639-63201226 (-)
CBA/J MGP_CBAJ_G0034584
 protein coding gene Chr9:66977880-67178412 (-)
DBA/2J MGP_DBA2J_G0034743
 protein coding gene Chr9:60715132-60896492 (-)
FVB/NJ MGP_FVBNJ_G0034685
 protein coding gene Chr9:60013406-60195445 (-)
LP/J MGP_LPJ_G0034826
 protein coding gene Chr9:63300749-63503174 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034728
 protein coding gene Chr9:68295892-68501382 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035444
 protein coding gene Chr9:62431107-62627882 (-)
PWK/PhJ MGP_PWKPhJ_G0033638
 protein coding gene Chr9:60855431-61040689 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033472
 protein coding gene Chr9:62707242-62896418 (-)
WSB/EiJ MGP_WSBEiJ_G0034047
 protein coding gene Chr9:62336133-62524656 (-)



Homology
more
  • Human Ortholog
    IQCH, IQ motif containing H
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IQCH, IQ motif containing H
  • Synonyms
    NYDSP5
  • Links
    NCBI Gene ID: 64799
    neXtProt AC: NX_Q86VS3
    UniProt: Q86VS3

  • Chr Location
    15q23; chr15:67254786-67502260 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 2 alleles in 2 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice lacking the DNA binding domain exhibit male infertility and show low sperm production and viability, reduced sperm motility, and sperm abnormalities including malformations of the acrosome.
Gene Ontology
(GO)
Classifications
less
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    6
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000037801 Ensembl Gene Model | MGI Sequence Detail 181039 C57BL/6J ±  kb
    transcript ENSMUST00000042322 Ensembl | MGI Sequence Detail 3672 Not Applicable  
    polypeptide ENSMUSP00000047953 Ensembl | MGI Sequence Detail 1071 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 8
      Genomic 2
      cDNA 6

      Microarray probesets 2
    References
    more
    • Summaries
      All 29
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory