Lhx1os Gene Detail

Summary

• Symbol
  Lhx1os
• Name
  LIM homeobox 1, opposite strand
• Synonyms
  1500016L03Rik, Lhx1as, ln-CR7

• Feature Type
  lncRNA gene
• IDs
  MGI:1925615
  NCBI Gene: 78365
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr11:84416486-84426657 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, 51.31 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  264 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1925615	lncRNA gene	Chr11:84416444-84430095 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0005271	lincRNA gene	Chr11:85947258-85957401 (+)
A/J	MGP_AJ_G0005256	lincRNA gene	Chr11:82678545-82689037 (+)
AKR/J	MGP_AKRJ_G0005234	lincRNA gene	Chr11:85126616-85136673 (+)
BALB/cJ	MGP_BALBcJ_G0005236	lincRNA gene	Chr11:83063710-83074346 (+)
C3H/HeJ	MGP_C3HHeJ_G0005185	lincRNA gene	Chr11:85184067-85194139 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0005388	lincRNA gene	Chr11:88565092-88575235 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0004781	lincRNA gene	Chr11:79763297-79773398 (+)
CAST/EiJ	MGP_CASTEiJ_G0005132	lincRNA gene	Chr11:85807313-85819115 (+)
CBA/J	MGP_CBAJ_G0005175	lincRNA gene	Chr11:92337071-92347226 (+)
DBA/2J	MGP_DBA2J_G0005192	lincRNA gene	Chr11:82259435-82269553 (+)
FVB/NJ	MGP_FVBNJ_G0005217	lincRNA gene	Chr11:81740842-81750981 (+)
LP/J	MGP_LPJ_G0005273	lincRNA gene	Chr11:86486075-86496253 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0005200	lincRNA gene	Chr11:92485863-92496032 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0005392	lincRNA gene	Chr11:85407573-85418726 (+)
PWK/PhJ	MGP_PWKPhJ_G0005081	lincRNA gene	Chr11:83023465-83033714 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0005003	lincRNA gene	Chr11:84952374-84962475 (+)
WSB/EiJ	MGP_WSBEiJ_G0005180	lincRNA gene	Chr11:85253126-85263194 (+)

Homology

• Gene Tree
  Lhx1os
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  1 phenotype from 1 allele in 1 genetic background
  10 phenotype references
  

• All Mutations and Alleles
  4
• Chemically induced (other)
  1
• Endonuclease-mediated
  2
• Targeted
  1
• Genomic Mutations
  2 involving Lhx1os
• Find Mice (IMSR)
  0 strains or lines available

Mice homozygous for a null allele are viable with no obvious defects.

Gene Ontology
(GO)
Classifications

Expression

• Assay Results
  779
• Tissues
  64
• cDNA Data
  9
• Literature Summary
  4

Images

Tissue x Stage Matrix

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  41
• RefSeq
  1

• Ensembl
  ENSMUSG00000087211 (Evidence)
• NCBI Gene
  78365

Representative Sequences			Length	Strain/Species
genomic	78365	NCBI Gene Model | MGI Sequence Detail	10172	C57BL/6J
transcript	NR_038057	RefSeq | MGI Sequence Detail	624	C57BL/6

Molecular
Reagents

• All nucleic 9

  cDNA 9

  
  

  Microarray probesets 1

References

• Summaries
  All 26

  Developmental Gene Expression 4

  Phenotypes 10
• Earliest
  J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
• Latest
  J:332662 Pellegrini F, et al., A KO mouse model for the lncRNA Lhx1os produces motor neuron alterations and locomotor impairment. iScience. 2023 Jan 20;26(1):105891

TSS for Lhx1os:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr103805	Chr11:84416473-84416484 (+)	-7 bp
Tssr103806	Chr11:84416498-84416515 (+)	21 bp