Snrnp25 Gene Detail

Summary

• Symbol
  Snrnp25
• Name
  small nuclear ribonucleoprotein 25 (U11/U12)
• Synonyms
  3300001G02Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1925622
  NCBI Gene: 78372
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr11:32155415-32158984 bp, + strand

  From Ensembl annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 11, 18.82 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  223 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1925622	protein coding gene	Chr11:32155415-32158996 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0018127	protein coding gene	Chr11:30402953-30406522 (+)
A/J	MGP_AJ_G0018100	protein coding gene	Chr11:29252016-29255603 (+)
AKR/J	MGP_AKRJ_G0018064	protein coding gene	Chr11:30175917-30181170 (+)
BALB/cJ	MGP_BALBcJ_G0018069	protein coding gene	Chr11:29447537-29451106 (+)
C3H/HeJ	MGP_C3HHeJ_G0017882	protein coding gene	Chr11:30125775-30129344 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0018521	protein coding gene	Chr11:31408220-31411789 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0016176	protein coding gene	Chr11:27785315-27789119 (+)
CAST/EiJ	MGP_CASTEiJ_G0017444	protein coding gene	Chr11:30156459-30160040 (+)
CBA/J	MGP_CBAJ_G0017855	protein coding gene	Chr11:32906687-32910494 (+)
DBA/2J	MGP_DBA2J_G0017965	protein coding gene	Chr11:29051571-29055158 (+)
FVB/NJ	MGP_FVBNJ_G0017959	protein coding gene	Chr11:28872408-28876922 (+)
LP/J	MGP_LPJ_G0018037	protein coding gene	Chr11:30638504-30642073 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0017983	protein coding gene	Chr11:33900057-33903626 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0018562	protein coding gene	Chr11:30310063-30313630 (+)
PWK/PhJ	MGP_PWKPhJ_G0017227	protein coding gene	Chr11:29201849-29205670 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0017021	protein coding gene	Chr11:30004212-30007733 (+)
WSB/EiJ	MGP_WSBEiJ_G0017497	protein coding gene	Chr11:29945205-29948783 (+)

Homology

• Human Ortholog
  SNRNP25, small nuclear ribonucleoprotein U11/U12 subunit 25

• Vertebrate Orthologs
  3

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  SNRNP25, small nuclear ribonucleoprotein U11/U12 subunit 25
  
• Synonyms
  C16orf33
• Links
  HGNC:14161

  NCBI Gene ID: 79622

  neXtProt AC: NX_Q9BV90

  UniProt: Q9BV90

  
  
• Chr Location
  16p13.3; chr16:53828-57669 (+)  GRCh38

---

• MGI Vertebrate Homology
  Snrnp25 stringent orthology
  1 human;1 mouse;1 rat;1 zebrafish
  
• HCOP
  vertebrate homology predictions: SNRNP25
• Gene Tree
  Snrnp25
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  6 phenotype references
  

• All Mutations and Alleles
  6
• Chemically induced (other)
  1
• Endonuclease-mediated
  2
• Targeted
  3
• Genomic Mutations
  1 involving Snrnp25
• Incidental Mutations
  Mutagenetix , APF , CvDC
• Find Mice (IMSR)
  10 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  8
• GO References
  5

Expression

• Assay Results
  726
• Tissues
  4
• cDNA Data
  43
• Literature Summary
  1

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase snrnp25

Sequences &
Gene Models

• All Sequences
  41
• RefSeq
  2
• UniProt
  4
• CCDS
  CCDS24518.1

• Ensembl
  ENSMUSG00000040767 (Evidence)
• NCBI Gene
  78372

Representative Sequences			Length	Strain/Species
genomic	ENSMUSG00000040767	Ensembl Gene Model | MGI Sequence Detail	3570	C57BL/6J
transcript	ENSMUST00000249622	Ensembl | MGI Sequence Detail	821	Not Applicable
polypeptide	ENSMUSP00000159831	Ensembl | MGI Sequence Detail	160	Not Applicable

Protein
Information

• UniProt
  4 Sequences
• Protein Ontology
  PR:000015333 U11/U12 small nuclear ribonucleoprotein 25 kDa protein
  (term hierarchy)
• PDB
  1V2Y
• InterPro Domains
  IPR040610 SNRNP25, ubiquitin-like domain
  IPR039690 U11/U12 small nuclear ribonucleoprotein 25kDa protein
  IPR029071 Ubiquitin-like domain superfamily

Molecular
Reagents

• All nucleic 44

  cDNA 43

  Primer pair 1

  
  

  Microarray probesets 3

Other
Accession IDs

MGI:2144360

References

• Summaries
  All 31

  Developmental Gene Expression 1

  Gene Ontology 5

  Phenotypes 6
• Earliest
  J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
• Latest
  J:137212 Pessa HK, et al., Minor spliceosome components are predominantly localized in the nucleus. Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8655-60

TSS for Snrnp25:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr100829	Chr11:32155411-32155481 (+)	31 bp
Tssr100830	Chr11:32155483-32155504 (+)	79 bp