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Zfp449 Gene Detail
Summary
  • Symbol
    Zfp449
  • Name
    zinc finger protein 449
  • Synonyms
    9530049C15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925869
    NCBI Gene: 78619
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:55391760-55411034 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 30.06 cM, cytoband A4
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    448 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925869
 protein coding gene ChrX:55391757-55411034 (+)
129S1/SvImJ MGP_129S1SvImJ_G0035732
 protein coding gene ChrX:51629999-51649154 (+)
A/J MGP_AJ_G0035715
 protein coding gene ChrX:51825754-51844891 (+)
AKR/J MGP_AKRJ_G0035636
 protein coding gene ChrX:53187854-53207169 (+)
BALB/cJ MGP_BALBcJ_G0035702
 protein coding gene ChrX:51298145-51317283 (+)
C3H/HeJ MGP_C3HHeJ_G0035405
 protein coding gene ChrX:52157204-52176340 (+)
C57BL/6NJ MGP_C57BL6NJ_G0036231
 protein coding gene ChrX:53005338-53022207 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0033083
 protein coding gene ChrX:51280004-51300127 (+)
CAST/EiJ MGP_CASTEiJ_G0034699
 protein coding gene ChrX:38043343-38064068 (+)
CBA/J MGP_CBAJ_G0035379
 protein coding gene ChrX:54534220-54555220 (+)
DBA/2J MGP_DBA2J_G0035534
 protein coding gene ChrX:51428862-51448106 (+)
FVB/NJ MGP_FVBNJ_G0035483
 protein coding gene ChrX:51026785-51045926 (+)
LP/J MGP_LPJ_G0035622
 protein coding gene ChrX:52218261-52237441 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0035522
 protein coding gene ChrX:56084433-56107318 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0036249
 protein coding gene ChrX:51663761-51682901 (+)
PWK/PhJ MGP_PWKPhJ_G0034395
 protein coding gene ChrX:36320596-36340080 (+)
SPRET/EiJ MGP_SPRETEiJ_G0034239
 protein coding gene ChrX:38785639-38805252 (+)
WSB/EiJ MGP_WSBEiJ_G0034842
 protein coding gene ChrX:51189694-51208965 (+)



Homology
more
  • Human Ortholog
    ZNF449, zinc finger protein 449
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF449, zinc finger protein 449
  • Synonyms
    ZSCAN19
  • Links
    NCBI Gene ID: 203523
    neXtProt AC: NX_Q6P9G9
    UniProt: Q6P9G9

  • Chr Location
    Xq26.3
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    2 phenotype references
Mice homozygous for a knock-out allele exhibit normal skeletal growth and cartilage homeostasis.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    761
  • Tissues
    50
  • cDNA Data
    17
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000073176 Ensembl Gene Model | MGI Sequence Detail 19275 C57BL/6J ±  kb
transcript ENSMUST00000101560 Ensembl | MGI Sequence Detail 3738 Not Applicable  
polypeptide ENSMUSP00000099096 Ensembl | MGI Sequence Detail 518 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 18
    cDNA 17
    Primer pair 1

    Microarray probesets 1
References
more
  • Summaries
    All 21
    Developmental Gene Expression 3
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:225376 Okada K, et al., Identification of SCAN domain zinc-finger gene ZNF449 as a novel factor of chondrogenesis. PLoS One. 2014;9(12):e115169
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory