About   Help   FAQ
Filip1l Gene Detail
Summary
  • Symbol
    Filip1l
  • Name
    filamin A interacting protein 1-like
  • Synonyms
    4631422O05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1925999
    NCBI Gene: 78749
  • Alliance
    gene page
  • Transcription Start Sites
    23 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:57173376-57393167 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 34.22 cM, cytoband C1.1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    5500 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1925999
 protein coding gene Chr16:57173376-57393489 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022899
 protein coding gene Chr16:56506348-56730120 (+)
A/J MGP_AJ_G0022866
 protein coding gene Chr16:54082083-54305176 (+)
AKR/J MGP_AKRJ_G0022838
 protein coding gene Chr16:55797624-56021012 (+)
BALB/cJ MGP_BALBcJ_G0022866
 protein coding gene Chr16:54188910-54412847 (+)
C3H/HeJ MGP_C3HHeJ_G0022629
 protein coding gene Chr16:55987502-56210770 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023314
 protein coding gene Chr16:58069358-58304896 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020825
 protein coding gene Chr16:53738311-53955217 (+)
CAST/EiJ MGP_CASTEiJ_G0022156
 protein coding gene Chr16:56370270-56607441 (+)
CBA/J MGP_CBAJ_G0022602
 protein coding gene Chr16:60424841-60668329 (+)
DBA/2J MGP_DBA2J_G0022734
 protein coding gene Chr16:53820128-54042396 (+)
FVB/NJ MGP_FVBNJ_G0022709
 protein coding gene Chr16:53591157-53812491 (+)
LP/J MGP_LPJ_G0022801
 protein coding gene Chr16:56315321-56534192 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022727
 protein coding gene Chr16:60759004-60987020 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023329
 protein coding gene Chr16:55937767-56162377 (+)
PWK/PhJ MGP_PWKPhJ_G0021895
 protein coding gene Chr16:54139764-54369361 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021725
 protein coding gene Chr16:55734585-55966531 (+)
WSB/EiJ MGP_WSBEiJ_G0022200
 protein coding gene Chr16:55982510-56211311 (+)



Homology
more
  • Human Ortholog
    FILIP1L, filamin A interacting protein 1 like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FILIP1L, filamin A interacting protein 1 like
  • Synonyms
    DOC-1, DOC1, GIP130, GIP90
  • Links
    NCBI Gene ID: 11259
    neXtProt AC: NX_Q4L180
    UniProt: Q4L180

  • Chr Location
    3q12.1; chr3:99828811-100114513 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    711
  • Tissues
    1
  • cDNA Data
    47
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 78749 NCBI Gene Model | MGI Sequence Detail 219792 C57BL/6J ±  kb
    transcript NM_001040397 RefSeq | MGI Sequence Detail 4206 C57BL/6  
    polypeptide Q6P6L0 UniProt | EBI | MGI Sequence Detail 1131 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      3 Sequences
    • Protein Ontology
      PR:000007525 filamin A-interacting protein 1-like
      (term hierarchy)
    • InterPro Domains
      IPR050719 Cortactin-binding and Actin Dynamics Regulator
      IPR019131 Cortactin-binding protein-2, N-terminal
    • GlyGen
      Q6P6L0 2 sites, 1 O-linked glycan (2 sites)
    Molecular
    Reagents
    less
    • All nucleic 49
      Genomic 2
      cDNA 47

      Microarray probesets 5
    References
    more
    • Summaries
      All 32
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 7
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:358302 Kang X, et al., Exercise-induced Musclin determines the fate of fibro-adipogenic progenitors to control muscle homeostasis. Cell Stem Cell. 2024 Feb 1;31(2):212-226.e7
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory