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Csgalnact2 Gene Detail
Summary
  • Symbol
    Csgalnact2
  • Name
    chondroitin sulfate N-acetylgalactosaminyltransferase 2
  • Synonyms
    4632415D10Rik, Galnact2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926002
    NCBI Gene: 78752
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:118084413-118116101 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 55.86 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    747 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926002
 protein coding gene Chr6:118084413-118116132 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031183
 protein coding gene Chr6:120846045-120877735 (-)
A/J MGP_AJ_G0031152
 protein coding gene Chr6:116219046-116250524 (-)
AKR/J MGP_AKRJ_G0031083
 protein coding gene Chr6:119347823-119372153 (-)
BALB/cJ MGP_BALBcJ_G0031163
 protein coding gene Chr6:115997540-116031396 (-)
C3H/HeJ MGP_C3HHeJ_G0030546
 protein coding gene Chr6:64914786-64947498 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031621
 protein coding gene Chr6:123962988-123994677 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028783
 protein coding gene Chr6:113147802-113182202 (-)
CAST/EiJ MGP_CASTEiJ_G0030270
 protein coding gene Chr6:119726016-119759483 (-)
CBA/J MGP_CBAJ_G0030846
 protein coding gene Chr6:128845195-128876887 (-)
DBA/2J MGP_DBA2J_G0031002
 protein coding gene Chr6:115122281-115154011 (-)
FVB/NJ MGP_FVBNJ_G0030954
 protein coding gene Chr6:114255132-114286763 (-)
LP/J MGP_LPJ_G0031081
 protein coding gene Chr6:120874633-120908588 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030988
 protein coding gene Chr6:132949681-132984559 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031650
 protein coding gene Chr6:119375793-119407523 (-)
PWK/PhJ MGP_PWKPhJ_G0029985
 protein coding gene Chr6:114137357-114169266 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029814
 protein coding gene Chr6:118097746-118129932 (-)
WSB/EiJ MGP_WSBEiJ_G0030353
 protein coding gene Chr6:119644033-119675756 (-)



Homology
more
  • Human Ortholog
    CSGALNACT2, chondroitin sulfate N-acetylgalactosaminyltransferase 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CSGALNACT2, chondroitin sulfate N-acetylgalactosaminyltransferase 2
  • Synonyms
    beta4GalNAcT, ChGn-2, CHGN2, GALNACT-2, GALNACT2, PRO0082
  • Links
    NCBI Gene ID: 55454
    neXtProt AC: NX_Q8N6G5
    UniProt: Q8N6G5

  • Chr Location
    10q11.21; chr10:43138445-43185308 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    20 phenotypes from multigenic genotypes
    9 phenotype references
Mice homozygous for a knock-out allele are viable and fertile with no gross abnormalities and normal skeletal morphology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    19
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    739
  • Tissues
    11
  • cDNA Data
    29
  • Literature Summary
    6
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042042 Ensembl Gene Model | MGI Sequence Detail 31689 C57BL/6J ±  kb
transcript ENSMUST00000049344 Ensembl | MGI Sequence Detail 3661 Not Applicable  
polypeptide ENSMUSP00000039819 Ensembl | MGI Sequence Detail 542 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    cDNA 29
    Primer pair 5
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 45
    Developmental Gene Expression 6
    Gene Ontology 12
    Phenotypes 9
  • Earliest
    J:324068 Silbert JE, et al., Biosynthesis of chondroitin sulphate by a Golgi-apparatus-enriched preparation from cultures of mouse mastocytoma cells. Biochem J. 1980 Aug 15;190(2):307-13
  • Latest
    J:318584 Adhikara IM, et al., Chondroitin Sulfate N-acetylgalactosaminyltransferase-2 Impacts Foam Cell Formation and Atherosclerosis by Altering Macrophage Glycosaminoglycan Chain. Arterioscler Thromb Vasc Biol. 2021 Mar;41(3):1076-1091
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory