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Sfi1 Gene Detail
Summary
  • Symbol
    Sfi1
  • Name
    Sfi1 homolog, spindle assembly associated (yeast)
  • Synonyms
    2310047I15Rik, mKIAA0542
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926137
    NCBI Gene: 78887
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:3081850-3143463 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 2.19 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    927 from dbSNP Build 142
  • Strain Annotations
    9
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926137
 protein coding gene Chr11:3081850-3153344 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017951
 protein coding gene Chr11:519-32535 (-)
A/J MGP_AJ_G0017924
 protein coding gene Chr11:5894-100929 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0017892
 protein coding gene Chr11:19982-75908 (-)
C3H/HeJ no annotation
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0016004
 protein coding gene Chr11:13911-21417 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0017680
 protein coding gene Chr11:87163-91882 (-)
DBA/2J MGP_DBA2J_G0017791
 protein coding gene Chr11:8387-23905 (-)
FVB/NJ MGP_FVBNJ_G0029210
 protein coding gene Chr5:29420761-29440709 (+)
LP/J no annotation
NOD/ShiLtJ no annotation
NZO/HlLtJ no annotation
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0016843
 protein coding gene Chr11:915-60485 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    SFI1, SFI1 centrin binding protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SFI1, SFI1 centrin binding protein
  • Synonyms
    hSfi1p, PISD, PPP1R139
  • Links
    NCBI Gene ID: 9814
    neXtProt AC: NX_A8K8P3
    UniProt: A8K8P3

  • Chr Location
    22q12.2; chr22:31488688-31618588 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    883
  • Tissues
    60
  • cDNA Data
    12
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000023764 Ensembl Gene Model | MGI Sequence Detail 61614 C57BL/6J ±  kb
transcript ENSMUST00000081318 Ensembl | MGI Sequence Detail 3969 Not Applicable  
polypeptide ENSMUSP00000080066 Ensembl | MGI Sequence Detail 1216 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 12

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 2
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory