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Car5b Gene Detail
Summary
  • Symbol
    Car5b
  • Name
    carbonic anhydrase 5b, mitochondrial
  • Synonyms
    7330410H16Rik, CAVB, D730005F19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926249
    NCBI Gene: 56078
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:162759818-162810993 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 76.03 cM, cytoband F5
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1382 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926249
 protein coding gene ChrX:162759818-162811006 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036249
 protein coding gene ChrX:162052965-162106246 (-)
A/J MGP_AJ_G0036219
 protein coding gene ChrX:161223305-161276368 (-)
AKR/J MGP_AKRJ_G0036147
 protein coding gene ChrX:166409784-166467442 (-)
BALB/cJ MGP_BALBcJ_G0036212
 protein coding gene ChrX:159225677-159278812 (-)
C3H/HeJ MGP_C3HHeJ_G0035918
 protein coding gene ChrX:162404425-162457389 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036734
 protein coding gene ChrX:166804073-166856981 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033556
 protein coding gene ChrX:152284156-152336341 (-)
CAST/EiJ MGP_CASTEiJ_G0035207
 protein coding gene ChrX:141374800-141427749 (-)
CBA/J MGP_CBAJ_G0035893
 protein coding gene ChrX:171623182-171685473 (-)
DBA/2J MGP_DBA2J_G0036059
 protein coding gene ChrX:160122275-160172876 (-)
FVB/NJ MGP_FVBNJ_G0035990
 protein coding gene ChrX:159254636-159304990 (-)
LP/J MGP_LPJ_G0036144
 protein coding gene ChrX:163197189-163246602 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0036022
 protein coding gene ChrX:180317173-180374700 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036775
 protein coding gene ChrX:161541218-161593487 (-)
PWK/PhJ MGP_PWKPhJ_G0034905
 protein coding gene ChrX:138163345-138216269 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034726
 protein coding gene ChrX:141878033-141936221 (-)
WSB/EiJ MGP_WSBEiJ_G0035342
 protein coding gene ChrX:159505097-159557959 (-)



Homology
more
  • Human Ortholog
    CA5B, carbonic anhydrase 5B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CA5B, carbonic anhydrase 5B
  • Synonyms
    CA-VB, CAVB
  • Links
    NCBI Gene ID: 11238
    neXtProt AC: NX_Q9Y2D0
    UniProt: Q9Y2D0

  • Chr Location
    Xp22.2; chrX:15688830-15788411 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    6 phenotypes from multigenic genotypes
    9 phenotype references
Mice that are either homozygous or hemizygous for a knock-out allele exhibit normal survival and show no detectable differences in blood ammonia or fasting glucose levels relative to control littermates.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    813
  • Tissues
    104
  • cDNA Data
    29
  • Literature Summary
    5
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031373 Ensembl Gene Model | MGI Sequence Detail 51176 C57BL/6J ±  kb
transcript ENSMUST00000033739 Ensembl | MGI Sequence Detail 3436 Not Applicable  
polypeptide ENSMUSP00000033739 Ensembl | MGI Sequence Detail 317 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 31
    cDNA 29
    Primer pair 2

    Microarray probesets 2
Other
Accession IDs
less
MGI:1925347, MGI:1926092
References
more
  • Summaries
    All 36
    Developmental Gene Expression 5
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:64692 Shah GN, et al., Mitochondrial carbonic anhydrase CA VB: differences in tissue distribution and pattern of evolution from those of CA VA suggest distinct physiological roles. Proc Natl Acad Sci U S A. 2000 Feb 15;97(4):1677-82
  • Latest
    J:294207 Gan P, et al., Allelic variants between mouse substrains BALB/cJ and BALB/cByJ influence mononuclear cardiomyocyte composition and cardiomyocyte nuclear ploidy. Sci Rep. 2020 May 5;10(1):7605
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory