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Mrpl37 Gene Detail
Summary
  • Symbol
    Mrpl37
  • Name
    mitochondrial ribosomal protein L37
  • Synonyms
    2300004O14Rik, MRP-L2, Rpml2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926268
    NCBI Gene: 56280
  • Alliance
    gene page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:106913071-106924063 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 49.99 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    358 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926268
 protein coding gene Chr4:106913071-106924065 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028529
 protein coding gene Chr4:107725545-107736560 (-)
A/J MGP_AJ_G0028492
 protein coding gene Chr4:103864071-103875065 (-)
AKR/J MGP_AKRJ_G0028439
 protein coding gene Chr4:106400457-106411451 (-)
BALB/cJ MGP_BALBcJ_G0028511
 protein coding gene Chr4:104054593-104065466 (-)
C3H/HeJ MGP_C3HHeJ_G0028225
 protein coding gene Chr4:107154234-107166255 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028951
 protein coding gene Chr4:111606568-111617558 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026242
 protein coding gene Chr4:99141817-99154162 (-)
CAST/EiJ MGP_CASTEiJ_G0027661
 protein coding gene Chr4:104967810-104980500 (-)
CBA/J MGP_CBAJ_G0028194
 protein coding gene Chr4:115219548-115231257 (-)
DBA/2J MGP_DBA2J_G0028342
 protein coding gene Chr4:103480975-103492213 (-)
FVB/NJ MGP_FVBNJ_G0028310
 protein coding gene Chr4:102349716-102360739 (-)
LP/J MGP_LPJ_G0028443
 protein coding gene Chr4:107923000-107933894 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028336
 protein coding gene Chr4:120521345-120532787 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028987
 protein coding gene Chr4:106642431-106653418 (-)
PWK/PhJ MGP_PWKPhJ_G0027387
 protein coding gene Chr4:101728128-101739413 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027211
 protein coding gene Chr4:104045664-104057078 (-)
WSB/EiJ MGP_WSBEiJ_G0027742
 protein coding gene Chr4:106827036-106837828 (-)



Homology
more
  • Human Ortholog
    MRPL37, mitochondrial ribosomal protein L37
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL37, mitochondrial ribosomal protein L37
  • Synonyms
    L2mt, L37mt, mL37, MRP-L2, MRPL2, MRP-L37, RPML2
  • Links
    NCBI Gene ID: 51253
    neXtProt AC: NX_Q9BZE1
    UniProt: Q9BZE1

  • Chr Location
    1p32.3; chr1:54184041-54225489 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    13
  • cDNA Data
    126
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56280 NCBI Gene Model | MGI Sequence Detail 10993 C57BL/6J ±  kb
transcript NM_025500 RefSeq | MGI Sequence Detail 1478 C57BL/6  
polypeptide Q921S7 UniProt | EBI | MGI Sequence Detail 423 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000010597 large ribosomal subunit protein mL37
    (term hierarchy)
  • InterPro Domains
    IPR010793 Large ribosomal subunit protein mL37/mL65
    IPR052482 Mitochondrial large ribosomal subunit mL37
  • GlyGen
    Q921S7 2 sites, 2 N-linked glycans (2 sites)
Molecular
Reagents
less
  • All nucleic 127
    cDNA 126
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1913592, MGI:2140198
References
more
  • Summaries
    All 42
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 13
  • Earliest
    J:64919 Graack HR, et al., Identification of mammalian mitochondrial ribosomal proteins (MRPs) by N-terminal sequencing of purified bovine MRPs and comparison to data bank sequences: the large subribosomal particle. Biochemistry. 1999 Dec 14;38(50):16569-77
  • Latest
    J:297050 Cheong A, et al., Expression analysis of mammalian mitochondrial ribosomal protein genes. Gene Expr Patterns. 2020 Sep 25;38:119147
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory