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Plac1 Gene Detail
Summary
  • Symbol
    Plac1
  • Name
    placental specific protein 1
  • Synonyms
    DXWsu72e, Epcs26, Oosp2l
  • Feature Type
    protein coding gene
  • IDs
    MGI:1926287
    NCBI Gene: 56096
  • Alliance
    gene page
  • Transcription Start Sites
    12 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:52158870-52328969 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 29.31 cM
  • Mapping Data
    8 experiments
Strain
Comparison
more
  • SNPs within 2kb
    3012 from dbSNP Build 142
  • Strain Annotations
    18
  • PCR
    1
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1926287
 protein coding gene ChrX:52158870-52328988 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035720
 protein coding gene ChrX:48314549-48489215 (-)
A/J MGP_AJ_G0035703
 protein coding gene ChrX:48162290-48335254 (-)
AKR/J MGP_AKRJ_G0035623
 protein coding gene ChrX:49490355-49687177 (-)
BALB/cJ MGP_BALBcJ_G0035689
 protein coding gene ChrX:47697287-47868365 (-)
C3H/HeJ MGP_C3HHeJ_G0035393
 protein coding gene ChrX:48565106-48740472 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036219
 protein coding gene ChrX:49460958-49640284 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033071
 protein coding gene ChrX:45628457-45795727 (-)
CAST/EiJ MGP_CASTEiJ_G0034684
 protein coding gene ChrX:36008331-36184185 (-)
CBA/J MGP_CBAJ_G0035367
 protein coding gene ChrX:50828133-51017648 (-)
DBA/2J MGP_DBA2J_G0035522
 protein coding gene ChrX:47941007-48112561 (-)
FVB/NJ MGP_FVBNJ_G0035470
 protein coding gene ChrX:47663888-47834975 (-)
LP/J MGP_LPJ_G0035609
 protein coding gene ChrX:48639679-48814563 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035509
 protein coding gene ChrX:52384933-52567252 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036236
 protein coding gene ChrX:48193768-48369335 (-)
PWK/PhJ MGP_PWKPhJ_G0034383
 protein coding gene ChrX:35499592-35673974 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034228
 protein coding gene ChrX:36833706-37017361 (-)
WSB/EiJ MGP_WSBEiJ_G0034828
 protein coding gene ChrX:47753662-47928808 (-)



Homology
more
  • Human Ortholog
    PLAC1, placenta enriched 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PLAC1, placenta enriched 1
  • Synonyms
    CT92, OOSP2B, OOSP2L
  • Links
    NCBI Gene ID: 10761
    neXtProt AC: NX_Q9HBJ0
    UniProt: Q9HBJ0

  • Chr Location
    Xq26.3; chrX:134565838-134764322 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotypes from 1 allele in 1 genetic background
    5 images
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Female and male mice null for this gene display postnatal lethality with placental abnormalities. Female mice heterozygous for this allele display an enlarged placenta with expansion of the junctional zone.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    824
  • Tissues
    66
  • cDNA Data
    33
  • Literature Summary
    14
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 56096 NCBI Gene Model | MGI Sequence Detail 170100 C57BL/6J ±  kb
    transcript NM_001426319 RefSeq | MGI Sequence Detail 1190 C57BL/6  
    polypeptide Q9JI83 UniProt | EBI | MGI Sequence Detail 173 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 39
      cDNA 33
      Primer pair 5
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGD-MRK-33931, MGI:106239, MGI:1860265
    References
    more
    • Summaries
      All 46
      Developmental Gene Expression 14
      Gene Ontology 3
      Phenotypes 9
    • Earliest
      J:50869 Ko MSH, et al., Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
    • Latest
      J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/17/2024
    MGI 6.24     		The Jackson Laboratory